Estimation and robustness analysis of protein networks for cell cycle systems

Takehito Azuma, Masachika Kurata, Noriko Takahashi, Shuichi Adachi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

This paper proposes an estimation problem of protein networks for cell cycle and their robustness analysis. Our proposed method is explained to estimate a protein network for cell cycle based on system identification techniques. The method is based on the least-squares method for state space models. Applying the method, a 6-dimensional protein network is estimated for cell cycle to demonstrate the efficacy of our proposed method. The estimated protein network is called as 6-dimensional cell cycle system and the cell cycle system is described as nonlinear differential equations. Moreover robustness analysis and numerical simulations are performed for the cell cycle system described as nonlinear differential equations. From these results, robustness of the cell cycle system is discussed.

Original languageEnglish
Title of host publicationProceedings of the IEEE International Conference on Control Applications
Pages512-517
Number of pages6
DOIs
Publication statusPublished - 2010
Event2010 IEEE International Conference on Control Applications, CCA 2010 - Yokohama, Japan
Duration: 2010 Sep 82010 Sep 10

Other

Other2010 IEEE International Conference on Control Applications, CCA 2010
CountryJapan
CityYokohama
Period10/9/810/9/10

Fingerprint

Cycle System
Robustness Analysis
Cell Cycle
Cells
Proteins
Protein
Nonlinear Differential Equations
Differential equations
State-space Model
System Identification
Least Square Method
Efficacy
Identification (control systems)
Robustness
Numerical Simulation
Computer simulation
Estimate

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Computer Science Applications
  • Mathematics(all)

Cite this

Azuma, T., Kurata, M., Takahashi, N., & Adachi, S. (2010). Estimation and robustness analysis of protein networks for cell cycle systems. In Proceedings of the IEEE International Conference on Control Applications (pp. 512-517). [5611122] https://doi.org/10.1109/CCA.2010.5611122

Estimation and robustness analysis of protein networks for cell cycle systems. / Azuma, Takehito; Kurata, Masachika; Takahashi, Noriko; Adachi, Shuichi.

Proceedings of the IEEE International Conference on Control Applications. 2010. p. 512-517 5611122.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Azuma, T, Kurata, M, Takahashi, N & Adachi, S 2010, Estimation and robustness analysis of protein networks for cell cycle systems. in Proceedings of the IEEE International Conference on Control Applications., 5611122, pp. 512-517, 2010 IEEE International Conference on Control Applications, CCA 2010, Yokohama, Japan, 10/9/8. https://doi.org/10.1109/CCA.2010.5611122
Azuma T, Kurata M, Takahashi N, Adachi S. Estimation and robustness analysis of protein networks for cell cycle systems. In Proceedings of the IEEE International Conference on Control Applications. 2010. p. 512-517. 5611122 https://doi.org/10.1109/CCA.2010.5611122
Azuma, Takehito ; Kurata, Masachika ; Takahashi, Noriko ; Adachi, Shuichi. / Estimation and robustness analysis of protein networks for cell cycle systems. Proceedings of the IEEE International Conference on Control Applications. 2010. pp. 512-517
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