Abstract
The change in oxy- and deoxy haemoglobin in the cortical tissue caused by brain function can be measured from multispectral images of exposed cortex. We cannot ignore the wavelength dependence of mean optical path length of detected light to calculate the accurate changes in concentrations of oxy- and deoxy- haemoglobin in the cortical tissue. The optical path length factor, which reflects the wavelength dependence of mean optical path length, is experimentally estimated from the multi-spectral images of exposed cortex of guinea pigs. The optical path length factor improves the accuracy in changes in concentrations of oxy- and deoxy-haemoglobin obtained from the multi-spectral images.
| Original language | English |
|---|---|
| Article number | 58590S |
| Pages (from-to) | 1-8 |
| Number of pages | 8 |
| Journal | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
| Volume | 5859 |
| Publication status | Published - 2005 |
| Event | Photon Migration and Diffuse-Light Imaging II - Munich, Germany Duration: 2005 Jun 12 → 2005 Jun 16 |
Keywords
- Exposed cortex
- Multi-spectral image
- Optical path length
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Biomaterials
- Radiology Nuclear Medicine and imaging