Estimation of path length factor for measurement of haemoglobin concentration in the exposed cortical tissue

K. Sakaguchi, T. Tachibana, K. Yokoyama, S. Furukawa, T. Katsura, A. Maki, H. Kawaguchi, E. Okada

    Research output: Contribution to journalConference article

    Abstract

    The change in oxy- and deoxy haemoglobin in the cortical tissue caused by brain function can be measured from multispectral images of exposed cortex. We cannot ignore the wavelength dependence of mean optical path length of detected light to calculate the accurate changes in concentrations of oxy- and deoxy- haemoglobin in the cortical tissue. The optical path length factor, which reflects the wavelength dependence of mean optical path length, is experimentally estimated from the multi-spectral images of exposed cortex of guinea pigs. The optical path length factor improves the accuracy in changes in concentrations of oxy- and deoxy-haemoglobin obtained from the multi-spectral images.

    Original languageEnglish
    Article number58590S
    Pages (from-to)1-8
    Number of pages8
    JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
    Volume5859
    Publication statusPublished - 2005 Dec 19
    EventPhoton Migration and Diffuse-Light Imaging II - Munich, Germany
    Duration: 2005 Jun 122005 Jun 16

    Keywords

    • Exposed cortex
    • Multi-spectral image
    • Optical path length

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Biomaterials
    • Atomic and Molecular Physics, and Optics
    • Radiology Nuclear Medicine and imaging

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