Estimation of path length factor for measurement of haemoglobin concentration in the exposed cortical tissue

K. Sakaguchi, T. Tachibana, K. Yokoyama, S. Furukawa, E. Okada, T. Katsura, A. Maki, H. Kawaguchi

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    The change in oxy- and deoxy haemoglobin in the cortical tissue caused by brain function can be measured from multi-spectral images of exposed cortex. We cannot ignore the wavelength dependence of mean optical path length of detected light to calculate the accurate changes in concentrations of oxy- and deoxy- haemoglobin in the cortical tissue. The optical path length factor, which reflects the wavelength dependence of mean optical path length, is experimentally estimated from the multi-spectral images of exposed cortex of guinea pigs. The optical path length factor improves the accuracy in changes in concentrations of oxy- and deoxy-haemoglobin obtained from the multi-spectral images.

    Original languageEnglish
    Title of host publicationEuropean Conference on Biomedical Optics, ECBO 2005
    PublisherOptical Society of America
    ISBN (Print)0819458635, 9780819458636
    Publication statusPublished - 2005 Jan 1
    EventEuropean Conference on Biomedical Optics, ECBO 2005 - Munich, Germany
    Duration: 2005 Jun 122005 Jun 12

    Publication series

    NameOptics InfoBase Conference Papers
    ISSN (Electronic)2162-2701

    Other

    OtherEuropean Conference on Biomedical Optics, ECBO 2005
    CountryGermany
    CityMunich
    Period05/6/1205/6/12

    ASJC Scopus subject areas

    • Instrumentation
    • Atomic and Molecular Physics, and Optics

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  • Cite this

    Sakaguchi, K., Tachibana, T., Yokoyama, K., Furukawa, S., Okada, E., Katsura, T., Maki, A., & Kawaguchi, H. (2005). Estimation of path length factor for measurement of haemoglobin concentration in the exposed cortical tissue. In European Conference on Biomedical Optics, ECBO 2005 (Optics InfoBase Conference Papers). Optical Society of America.