Abstract
This paper describes a method of producing a rotating flagella array. Flagella of unicellular algae Chlamydomonas were released from the cell body, and selectively fixed on the glass substrate where methacryloyloxyethylphosphorylcholine (MPC)-polymer was patterned in order to prevent non-specific binding. They were then reactivated and rotated like micro motors when ATP was added. Using this experimental set-up, we monitored single flagellum continuously on site and changed its rotating speed by controlling the concentration of Ca2+. We believe that rotating flagella can be utilized as actuators for various microfluidic devices.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 |
| Editors | Jean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1222-1224 |
| Number of pages | 3 |
| ISBN (Electronic) | 9780979806407 |
| Publication status | Published - 2007 |
| Event | 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France Duration: 2007 Oct 7 → 2007 Oct 11 |
Publication series
| Name | Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 |
|---|
Conference
| Conference | 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 |
|---|---|
| Country | France |
| City | Paris |
| Period | 07/10/7 → 07/10/11 |
Keywords
- Biomolecular motor
- Flagella
- Micro array
- MPC-polymer
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering
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Cite this
Nakamura, H., Kuribayashi, K., Onoe, H., & Takeuchi, S. (2007). Eukaryotic flagella as motile tools for microfluidic devices. In J-L. Viovy, P. Tabeling, S. Descroix, & L. Malaquin (Eds.), Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 (pp. 1222-1224). (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007). Chemical and Biological Microsystems Society.