Evaluation methodology of gas permeable characterization in a polymer-based microfluidic device by confocal fluorescence imaging

Mitsuhisa Ichiyanagi, Keita Sakai, Shinya Kidani, Yasuhiro Kakinuma, Yohei Sato, Koichi Hishida

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The evaluation technique of gas permeable characterization has been developed for an increased efficiency of gasliquid chemical reactions and high accuracy of environmental diagnosis. This technique enables us to measure spatial distributions of velocity and dissolved gas concentration by utilizing confocal micron-resolution particle image velocimetry combined with a laser-induced fluorescence technique. Microfluidic devices with gas permeability through polymer membranes are composed of a cover glass and a polydimethylsiloxane (PDMS) chip with the ability to permeate various gases, since PDMS is an elastomeric material. In the chip, microchannels are manufactured using a cryogenic micromachining system. The gas permeation is dominated by several factors, such as the gas and liquid flow rates, the membrane thickness between the gas and liquid flow, and the surface area of the membranes. The advantage of the present device is to realize the control of gas permeability by changing the surface roughness of PDMS, because the cryogenic micromachining enables us to control the surface roughness of microchannels and an increase in roughness yields an increase in the surface area of membranes. The experiments were performed under several conditions with a change in the gas flow rate, the PDMS membrane thickness and the surface roughness, which affect the gas permeation phenomena. The spatial distributions of velocity and dissolved gas concentration were measured in the liquid flow fields. The results indicate that the velocity-vector distributions have similar patterns under all experimental conditions, while the dissolved gas concentration distributions have different patterns. It was observed that the gas permeability through PDMS membranes increased with an increase in gas flow rates and surface roughness and with a decrease in membrane thicknesses, which is in qualitative agreement with membrane theory. The important conclusion is that the proposed technique is suggested to have the possibility of evaluating the characterization of gas permeable microfluidic device through membranes.

Original languageEnglish
Article number065023
JournalJournal of Micromechanics and Microengineering
Volume22
Issue number6
DOIs
Publication statusPublished - 2012 Jun

Fingerprint

Microfluidics
Polymers
Gases
Fluorescence
Imaging techniques
Membranes
Polydimethylsiloxane
Surface roughness
Gas permeability
Flow rate
Micromachining
Microchannels
Permeation
Cryogenics
Spatial distribution
Flow of gases
Liquids
Velocity measurement
Chemical reactions
Flow fields

ASJC Scopus subject areas

  • Mechanical Engineering
  • Electrical and Electronic Engineering
  • Mechanics of Materials
  • Electronic, Optical and Magnetic Materials

Cite this

Evaluation methodology of gas permeable characterization in a polymer-based microfluidic device by confocal fluorescence imaging. / Ichiyanagi, Mitsuhisa; Sakai, Keita; Kidani, Shinya; Kakinuma, Yasuhiro; Sato, Yohei; Hishida, Koichi.

In: Journal of Micromechanics and Microengineering, Vol. 22, No. 6, 065023, 06.2012.

Research output: Contribution to journalArticle

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