Evaluation of influence of anisotropic diffusion near a wall in near-field fluorescence correlation spectroscopy of nanoparticles

Kazuo Kasahara, Toshiharu Saiki

Research output: Contribution to journalArticlepeer-review

Abstract

Fluorescence correlation spectroscopy (FCS) of colloidal nanoparticles using a near-field fiber probe was numerically simulated. The near-wall dynamics was simulated by accounting for the anisotropic mobility of nanoparticles owing to hydrodynamic interaction with a wall (Stokes viscous force). By comparing the simulation results with theoretical model calculations, we found that the influence of anisotropic diffusion is insignificant in near-field FCS autocorrelation analysis.

Original languageEnglish
Pages (from-to)237-240
Number of pages4
JournalOptical Review
Volume18
Issue number2
DOIs
Publication statusPublished - 2011 Mar

Keywords

  • diffusion coefficient
  • fluorescence correlation spectroscopy
  • hydrodynamics
  • near-field optical microscopy

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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