Evaluation of renal function using 99mTc-MAG3 comparison with 131I-OIH by simultaneous dual energy peak acquisition method

T. Hashimoto, K. Matsumoto, R. Ishibashi, R. Iwasaki, T. Sanmiya, J. Hashimoto, E. Kunieda, K. Nakamura, A. Kubo

Research output: Contribution to journalArticlepeer-review


A newly developed 99mTc-labeled renal scintigraphic and renographic agent, 99mTc-mercaptoacetyltriglycine (99mTc-MAG3) was studied clinically and compared with 131I-OIH in 16 patients with various renal and urinary tract disorders. The abdominal aorta and the common iliac artery were clearly visualized in the vascular phase. The renogram patterns showed the same pattern in all cases. The parameters on the renogram such as T(max), T(2/3), T( 1/2 ) were compared. The highly significant correlations of T(max), T(2/3) and T( 1/2 ) were observed between 99mTc-MAG3 and 131I-OIH with correlation coefficient of 0.982, 0.907, 0.990, respectively. In all cases, excretion of 99mTc-MAG3 was slower than that of 131I-OIH and the ratios of T(max), T(2/3) and T( 1/2 ) between 99mTc-MAG3 and 131I-OIH were 1.113 ± 0.121, 1.277 ± 0.247, 1.179 ± 0.075, respectively. It is concluded that 99mTc-MAG3 is a useful renal imaging agent as an alternative to 131I or 123I-OIH.

Original languageEnglish
Pages (from-to)139-146
Number of pages8
Issue number2
Publication statusPublished - 1995 Jan 1


  • I-OIH
  • Tc-Mag
  • renogram
  • simultaneous injection

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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