Evaluation of safety and efficacy of transjugular liver biopsy in allogeneic hematopoietic stem cell transplant recipients

Taku Kikuchi, Takehiko Mori, Yuya Koda, Masuho Saburi, Sumiko Kohashi, Takaaki Toyama, Jun Kato, Subaru Hashimoto, Masayuki Nakatsuka, Hirotoshi Ebinuma, Shinichiro Okamoto

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We retrospectively evaluated the safety and utility of transjugular liver biopsy (TJLB) in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Ten patients underwent HSCT between 1991 and 2013. Eight patients with thrombocytopenia received platelet transfusions before and/or during TJLB. No complications associated with TJLB were observed. Samples adequate for a pathological diagnosis were obtained in 9 of the 10 patients, and the diagnoses made by TJLB were graft-versus-host-disease in eight patients and non-specific hepatitis in one. These results suggest that TJLB is a safe and effective procedure for the evaluation of liver injury in HSCT recipients.

Original languageEnglish
Pages (from-to)2320-2323
Number of pages4
Journal[Rinshō ketsueki] The Japanese journal of clinical hematology
Volume55
Issue number11
Publication statusPublished - 2014 Nov 1

ASJC Scopus subject areas

  • Medicine(all)

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