Evaluation of the E Test: A new quantitative antimicrobial susceptibility test. 2. Application for Streptococcus pneumoniae and Haemophilus influenzae strains

M. Hasegawa, U. Uchino, H. Muraoka, I. Kobayashi, A. Kaneko, J. Sasaki, S. Iwata

Research output: Contribution to journalArticle

Abstract

The E Test was applied to the MIC determination of different antimicrobial drugs for Streptococcus pneumoniae and Haemophilus influenzae strains isolated from pediatric infections. The E Test MICs were compared with those determined by the agar dilution method. The MIC values obtained by both methods were in agreement, regardless of the penicillin-susceptibility of the test strains or their β-lactamase producibility. However, the E Test MICs of imipenem, azithromycin and vancomycin for penicillin-insensitive strains of S. pneumoniae were one dilution higher than those determined by the agar dilution method. The E Test MICs were not affected by the addition of blood components. The E Test appears to be a reliable method for the determination of fastidious bacteria such as S. pneumoniae and H. influenzae.

Original languageEnglish
Pages (from-to)630-633
Number of pages4
JournalJapanese Journal of Chemotherapy
Volume43
Issue number6
Publication statusPublished - 1995 Jan 1

Keywords

  • H. influenzae
  • MIC
  • S. pneumoniae
  • Test

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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