Abstract
A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC-2 (CD99) positive tumor cells, and EWS-FLI-1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow-up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis.
| Original language | English |
|---|---|
| Pages (from-to) | 180-183 |
| Number of pages | 4 |
| Journal | Pediatric Blood and Cancer |
| Volume | 50 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2008 Jan |
| Externally published | Yes |
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Keywords
- Electron microscopy
- Ewing sarcoma/primitive neuroectodermal tumor
- EWS-FLI-1
- Immunohistochemistry
- Kidney
ASJC Scopus subject areas
- Cancer Research
- Pediatrics, Perinatology, and Child Health
- Hematology
Cite this
Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child. / Maeda, Miho; Tsuda, Akio; Yamanishi, Shingo; Uchikoba, Yoko; Fukunaga, Yoshitaka; Okita, Hajime; Hata, Jun Ichi.
In: Pediatric Blood and Cancer, Vol. 50, No. 1, 01.2008, p. 180-183.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child
AU - Maeda, Miho
AU - Tsuda, Akio
AU - Yamanishi, Shingo
AU - Uchikoba, Yoko
AU - Fukunaga, Yoshitaka
AU - Okita, Hajime
AU - Hata, Jun Ichi
PY - 2008/1
Y1 - 2008/1
N2 - A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC-2 (CD99) positive tumor cells, and EWS-FLI-1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow-up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis.
AB - A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC-2 (CD99) positive tumor cells, and EWS-FLI-1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow-up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis.
KW - Electron microscopy
KW - Ewing sarcoma/primitive neuroectodermal tumor
KW - EWS-FLI-1
KW - Immunohistochemistry
KW - Kidney
UR - http://www.scopus.com/inward/record.url?scp=36849054304&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=36849054304&partnerID=8YFLogxK
U2 - 10.1002/pbc.20831
DO - 10.1002/pbc.20831
M3 - Article
C2 - 16544300
AN - SCOPUS:36849054304
VL - 50
SP - 180
EP - 183
JO - Pediatric Blood and Cancer
JF - Pediatric Blood and Cancer
SN - 1545-5009
IS - 1
ER -