Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child

Miho Maeda, Akio Tsuda, Shingo Yamanishi, Yoko Uchikoba, Yoshitaka Fukunaga, Hajime Okita, Jun Ichi Hata

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC-2 (CD99) positive tumor cells, and EWS-FLI-1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow-up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis.

Original languageEnglish
Pages (from-to)180-183
Number of pages4
JournalPediatric Blood and Cancer
Volume50
Issue number1
DOIs
Publication statusPublished - 2008 Jan
Externally publishedYes

Fingerprint

Primitive Neuroectodermal Tumors
Ewing's Sarcoma
Kidney
Phosphopyruvate Hydratase
Lactose
Nephrectomy
Abdomen
Abdominal Pain
Neoplasms
Histology
Oxidoreductases
Necrosis
Tomography
Recurrence
Drug Therapy
EWS-FLI fusion protein

Keywords

  • Electron microscopy
  • Ewing sarcoma/primitive neuroectodermal tumor
  • EWS-FLI-1
  • Immunohistochemistry
  • Kidney

ASJC Scopus subject areas

  • Cancer Research
  • Pediatrics, Perinatology, and Child Health
  • Hematology

Cite this

Maeda, M., Tsuda, A., Yamanishi, S., Uchikoba, Y., Fukunaga, Y., Okita, H., & Hata, J. I. (2008). Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child. Pediatric Blood and Cancer, 50(1), 180-183. https://doi.org/10.1002/pbc.20831

Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child. / Maeda, Miho; Tsuda, Akio; Yamanishi, Shingo; Uchikoba, Yoko; Fukunaga, Yoshitaka; Okita, Hajime; Hata, Jun Ichi.

In: Pediatric Blood and Cancer, Vol. 50, No. 1, 01.2008, p. 180-183.

Research output: Contribution to journalArticle

Maeda, M, Tsuda, A, Yamanishi, S, Uchikoba, Y, Fukunaga, Y, Okita, H & Hata, JI 2008, 'Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child', Pediatric Blood and Cancer, vol. 50, no. 1, pp. 180-183. https://doi.org/10.1002/pbc.20831
Maeda, Miho ; Tsuda, Akio ; Yamanishi, Shingo ; Uchikoba, Yoko ; Fukunaga, Yoshitaka ; Okita, Hajime ; Hata, Jun Ichi. / Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child. In: Pediatric Blood and Cancer. 2008 ; Vol. 50, No. 1. pp. 180-183.
@article{6923fe973c6c4de797a10141cb89756a,
title = "Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child",
abstract = "A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC-2 (CD99) positive tumor cells, and EWS-FLI-1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow-up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis.",
keywords = "Electron microscopy, Ewing sarcoma/primitive neuroectodermal tumor, EWS-FLI-1, Immunohistochemistry, Kidney",
author = "Miho Maeda and Akio Tsuda and Shingo Yamanishi and Yoko Uchikoba and Yoshitaka Fukunaga and Hajime Okita and Hata, {Jun Ichi}",
year = "2008",
month = "1",
doi = "10.1002/pbc.20831",
language = "English",
volume = "50",
pages = "180--183",
journal = "Pediatric Blood and Cancer",
issn = "1545-5009",
publisher = "Wiley-Liss Inc.",
number = "1",

}

TY - JOUR

T1 - Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child

AU - Maeda, Miho

AU - Tsuda, Akio

AU - Yamanishi, Shingo

AU - Uchikoba, Yoko

AU - Fukunaga, Yoshitaka

AU - Okita, Hajime

AU - Hata, Jun Ichi

PY - 2008/1

Y1 - 2008/1

N2 - A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC-2 (CD99) positive tumor cells, and EWS-FLI-1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow-up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis.

AB - A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC-2 (CD99) positive tumor cells, and EWS-FLI-1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow-up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis.

KW - Electron microscopy

KW - Ewing sarcoma/primitive neuroectodermal tumor

KW - EWS-FLI-1

KW - Immunohistochemistry

KW - Kidney

UR - http://www.scopus.com/inward/record.url?scp=36849054304&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=36849054304&partnerID=8YFLogxK

U2 - 10.1002/pbc.20831

DO - 10.1002/pbc.20831

M3 - Article

C2 - 16544300

AN - SCOPUS:36849054304

VL - 50

SP - 180

EP - 183

JO - Pediatric Blood and Cancer

JF - Pediatric Blood and Cancer

SN - 1545-5009

IS - 1

ER -