Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child

Miho Maeda; Akio Tsuda; Shingo Yamanishi; Yoko Uchikoba; Yoshitaka Fukunaga; Hajime Okita; Jun Ichi Hata

doi:10.1002/pbc.20831

Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child

Miho Maeda, Akio Tsuda, Shingo Yamanishi, Yoko Uchikoba, Yoshitaka Fukunaga, Hajime Okita, Jun Ichi Hata

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC-2 (CD99) positive tumor cells, and EWS-FLI-1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow-up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis.

Original language	English
Pages (from-to)	180-183
Number of pages	4
Journal	Pediatric Blood and Cancer
Volume	50
Issue number	1
DOIs	https://doi.org/10.1002/pbc.20831
Publication status	Published - 2008 Jan
Externally published	Yes

Keywords

EWS-FLI-1
Electron microscopy
Ewing sarcoma/primitive neuroectodermal tumor
Immunohistochemistry
Kidney

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

Access to Document

10.1002/pbc.20831

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Cite this

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title = "Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child",

abstract = "A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC-2 (CD99) positive tumor cells, and EWS-FLI-1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow-up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis.",

keywords = "EWS-FLI-1, Electron microscopy, Ewing sarcoma/primitive neuroectodermal tumor, Immunohistochemistry, Kidney",

author = "Miho Maeda and Akio Tsuda and Shingo Yamanishi and Yoko Uchikoba and Yoshitaka Fukunaga and Hajime Okita and Hata, {Jun Ichi}",

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AU - Tsuda, Akio

AU - Yamanishi, Shingo

AU - Uchikoba, Yoko

AU - Fukunaga, Yoshitaka

AU - Okita, Hajime

AU - Hata, Jun Ichi

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