Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child

Miho Maeda; Akio Tsuda; Shingo Yamanishi; Yoko Uchikoba; Yoshitaka Fukunaga; Hajime Okita; Jun Ichi Hata

doi:10.1002/pbc.20831

Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child

Miho Maeda, Akio Tsuda, Shingo Yamanishi, Yoko Uchikoba, Yoshitaka Fukunaga, Hajime Okita, Jun Ichi Hata

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC-2 (CD99) positive tumor cells, and EWS-FLI-1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow-up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis.

Original language	English
Pages (from-to)	180-183
Number of pages	4
Journal	Pediatric Blood and Cancer
Volume	50
Issue number	1
DOIs	https://doi.org/10.1002/pbc.20831
Publication status	Published - 2008 Jan
Externally published	Yes

Keywords

EWS-FLI-1
Electron microscopy
Ewing sarcoma/primitive neuroectodermal tumor
Immunohistochemistry
Kidney

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

Access to Document

10.1002/pbc.20831

Cite this

@article{6923fe973c6c4de797a10141cb89756a,

title = "Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child",

abstract = "A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC-2 (CD99) positive tumor cells, and EWS-FLI-1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow-up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis.",

keywords = "EWS-FLI-1, Electron microscopy, Ewing sarcoma/primitive neuroectodermal tumor, Immunohistochemistry, Kidney",

author = "Miho Maeda and Akio Tsuda and Shingo Yamanishi and Yoko Uchikoba and Yoshitaka Fukunaga and Hajime Okita and Hata, {Jun Ichi}",

year = "2008",

month = jan,

doi = "10.1002/pbc.20831",

language = "English",

volume = "50",

pages = "180--183",

journal = "Medical and Pediatric Oncology",

issn = "1545-5009",

publisher = "Wiley-Liss Inc.",

number = "1",

}

TY - JOUR

T1 - Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child

AU - Maeda, Miho

AU - Tsuda, Akio

AU - Yamanishi, Shingo

AU - Uchikoba, Yoko

AU - Fukunaga, Yoshitaka

AU - Okita, Hajime

AU - Hata, Jun Ichi

PY - 2008/1

Y1 - 2008/1

N2 - A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC-2 (CD99) positive tumor cells, and EWS-FLI-1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow-up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis.

AB - A 6-year-old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC-2 (CD99) positive tumor cells, and EWS-FLI-1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow-up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis.

KW - EWS-FLI-1

KW - Electron microscopy

KW - Ewing sarcoma/primitive neuroectodermal tumor

KW - Immunohistochemistry

KW - Kidney

UR - http://www.scopus.com/inward/record.url?scp=36849054304&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=36849054304&partnerID=8YFLogxK

U2 - 10.1002/pbc.20831

DO - 10.1002/pbc.20831

M3 - Article

C2 - 16544300

AN - SCOPUS:36849054304

VL - 50

SP - 180

EP - 183

JO - Medical and Pediatric Oncology

JF - Medical and Pediatric Oncology

SN - 1545-5009

IS - 1

ER -

Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this