Ewing sarcoma/primitive neuroectodermal tumor of the kidney treated with chemotherapy including ifosfamide

Hiroki Yoshihara, Takahiro Kamiya, Yosuke Hosoya, Daisuke Hasegawa, Chitose Ogawa, Hiroshi Asanuma, Ryuichi Mizuno, Ryota Hosoya, Atsushi Manabe

Research output: Contribution to journalArticle

Abstract

Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) of the kidney is extremely rare, and is usually diagnosed after nephrectomy without neoadjuvant chemotherapy. Although ifosfamide and etoposide improve survival to a great extent in ES/PNET, the use of nephrotoxic agent, particularly ifosfamide, is a concern after nephrectomy. We describe the case of a 14-year-old female patient with abdominal mass who was diagnosed with ES/PNET of the right kidney after nephrectomy. Adjuvant chemotherapy including ifosfamide and etoposide were given. The estimated glomerular filtration rate decreased to 75% after the end of therapy. There was no evidence of recurrence 70 months after initial diagnosis.

Original languageEnglish
Pages (from-to)766-769
Number of pages4
JournalPediatrics International
Volume58
Issue number8
DOIs
Publication statusPublished - 2016 Aug 1

Fingerprint

Primitive Neuroectodermal Tumors
Ifosfamide
Ewing's Sarcoma
Nephrectomy
Etoposide
Kidney
Drug Therapy
Adjuvant Chemotherapy
Glomerular Filtration Rate
Recurrence
Survival
Therapeutics

Keywords

  • drug toxicity
  • Ewing sarcoma
  • ifosfamide
  • primitive neuroectodermal tumor
  • renal tumor

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Ewing sarcoma/primitive neuroectodermal tumor of the kidney treated with chemotherapy including ifosfamide. / Yoshihara, Hiroki; Kamiya, Takahiro; Hosoya, Yosuke; Hasegawa, Daisuke; Ogawa, Chitose; Asanuma, Hiroshi; Mizuno, Ryuichi; Hosoya, Ryota; Manabe, Atsushi.

In: Pediatrics International, Vol. 58, No. 8, 01.08.2016, p. 766-769.

Research output: Contribution to journalArticle

Yoshihara, Hiroki ; Kamiya, Takahiro ; Hosoya, Yosuke ; Hasegawa, Daisuke ; Ogawa, Chitose ; Asanuma, Hiroshi ; Mizuno, Ryuichi ; Hosoya, Ryota ; Manabe, Atsushi. / Ewing sarcoma/primitive neuroectodermal tumor of the kidney treated with chemotherapy including ifosfamide. In: Pediatrics International. 2016 ; Vol. 58, No. 8. pp. 766-769.
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