Executive dysfunction in remitted late-life depression: Juntendo University Mood Disorder Projects (JUMP)

Kanako Baba, Hajime Baba, Iwahide Noguchi, Reiko Arai, Toshihito Suzuki, Masaru Mimura, Heii Arai

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The authors aimed to investigate whether remitted adult and elderly major depressive disorder patients show different patterns of executive dysfunction. Executive functions of 20 euthymic major depressive disorder patients and 29 healthy comparison subjects were evaluated using the Behavioral Assessment of the Dysexecutive Syndrome. Relative to adult patients and healthy comparison subjects, euthymic elderly patients were more impaired in the subtest of Modified Six Elements. Since the regions most implicated in this subtest are the medial prefrontal, the anterior cingulate, and the dorsolateral prefrontal areas, the authors conclude that dysfunctions of such frontal neural networks remain unresolved even in the remission phase of late-life depression.

Original languageEnglish
Pages (from-to)70-74
Number of pages5
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume22
Issue number1
DOIs
Publication statusPublished - 2010 Jan 1
Externally publishedYes

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ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

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