TY - JOUR
T1 - Exercise-induced asthma is associated with impaired quality of life amon children with asthma in Japan
AU - Kojima, Namiko
AU - Ohya, Yukihiro
AU - Futamura, Masaki
AU - Akashi, Masayuki
AU - Odajima, Hiroshi
AU - Adachi, Yuichi
AU - Kobayashi, Fumio
AU - Akasawa, Akira
N1 - Funding Information:
This study was funded in part by Health and Labour Sciences Research Grants, Research on Allergic Disease and Immunology from the Ministry of Health, Labour and Welfare, Japan. The authors thank Kazuo Akiyama, Kiyoshi Takahashi, Takemasa Nakagawa, Akira Eboshida, Hiroyuki Nakamura (Japanese Asthma Survey Group) for helpful comments. The voluntary participation of all subjects in the study is sincerely appreciated.
PY - 2009
Y1 - 2009
N2 - Background: Asthma is the most common chronic diseases in school-aged children in Japan. It is important to consider health-related quality of life (QoL) among children with chronic diseases when treatment decisions are made. Methods: A school-based survey was conducted in randomly selected public schools in Tokyo by using a KINDL® questionnaire for evaluating QoL and the international study of asthma and allergy on childhood (ISAAC) questionnaire, which is designed for comparing the asthma prevalence in various countries, from May to June in 2005. We recruited approximately 10% of the total children 6-7-years-old and 13-14-years-old living in Tokyo for sampling. Results: Response rate of this questionnaire was 86% (22,645 children) in the 6-7-year-old group and 64% (12,879 children) in the 13-14-year-old group. Comparing asthmatics with non-asthmatics in the same age, QoL of children with asthma was significantly impaired. The severity of QoL of children with asthma was significantly impaired. QoL of children with exercise-induced asthma (EIA) were more significantly impaired than ones without EIA and showed lower scores in the categories of physical functioning, emotional and school activities than those without EIA. Of note, QoL was more impaired in the EIA-positive group among severe asthmatics, suggesting that QoL of children with even severe asthma could be improved when EIA is appropriately controlled. Conclusions: Existence of EIA among asthmatic children most strongly impairs their QoL. We should be more cautious about the management of EIA.
AB - Background: Asthma is the most common chronic diseases in school-aged children in Japan. It is important to consider health-related quality of life (QoL) among children with chronic diseases when treatment decisions are made. Methods: A school-based survey was conducted in randomly selected public schools in Tokyo by using a KINDL® questionnaire for evaluating QoL and the international study of asthma and allergy on childhood (ISAAC) questionnaire, which is designed for comparing the asthma prevalence in various countries, from May to June in 2005. We recruited approximately 10% of the total children 6-7-years-old and 13-14-years-old living in Tokyo for sampling. Results: Response rate of this questionnaire was 86% (22,645 children) in the 6-7-year-old group and 64% (12,879 children) in the 13-14-year-old group. Comparing asthmatics with non-asthmatics in the same age, QoL of children with asthma was significantly impaired. The severity of QoL of children with asthma was significantly impaired. QoL of children with exercise-induced asthma (EIA) were more significantly impaired than ones without EIA and showed lower scores in the categories of physical functioning, emotional and school activities than those without EIA. Of note, QoL was more impaired in the EIA-positive group among severe asthmatics, suggesting that QoL of children with even severe asthma could be improved when EIA is appropriately controlled. Conclusions: Existence of EIA among asthmatic children most strongly impairs their QoL. We should be more cautious about the management of EIA.
KW - Asthma
KW - Children
KW - Exercise induced asthma
KW - Health related QoL
KW - ISAAC
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U2 - 10.2332/allergolint.08-OA-0034
DO - 10.2332/allergolint.08-OA-0034
M3 - Article
C2 - 19240375
AN - SCOPUS:67651148391
VL - 58
SP - 187
EP - 192
JO - Allergology International
JF - Allergology International
SN - 1323-8930
IS - 2
ER -