Expanding stereochemical and skeletal diversity using petasis reactions and 1,3-dipolar cycloadditions

Giovanni Muncipinto; Taner Kaya; J. Anthony Wilson; Naoya Kumagai; Paul A. Clemons; Stuart L. Schreiber

doi:10.1021/ol102266j

Expanding stereochemical and skeletal diversity using petasis reactions and 1,3-dipolar cycloadditions

Giovanni Muncipinto, Taner Kaya, J. Anthony Wilson, Naoya Kumagai, Paul A. Clemons, Stuart L. Schreiber

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

A short and modular synthetic pathway using intramolecular 1,3-dipolar cycloaddition reactions and yielding functionalized isoxazoles, isoxazolines, and isoxazolidines is described. The change in shape of previous compounds and those in this study is quantified and compared using principal moment-of-inertia shape analysis.

Original language	English
Pages (from-to)	5230-5233
Number of pages	4
Journal	Organic Letters
Volume	12
Issue number	22
DOIs	https://doi.org/10.1021/ol102266j
Publication status	Published - 2010 Nov 19
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol102266j

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abstract = "A short and modular synthetic pathway using intramolecular 1,3-dipolar cycloaddition reactions and yielding functionalized isoxazoles, isoxazolines, and isoxazolidines is described. The change in shape of previous compounds and those in this study is quantified and compared using principal moment-of-inertia shape analysis.",

author = "Giovanni Muncipinto and Taner Kaya and Wilson, {J. Anthony} and Naoya Kumagai and Clemons, {Paul A.} and Schreiber, {Stuart L.}",

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AU - Muncipinto, Giovanni

AU - Kaya, Taner

AU - Wilson, J. Anthony

AU - Kumagai, Naoya

AU - Clemons, Paul A.

AU - Schreiber, Stuart L.

PY - 2010/11/19

Y1 - 2010/11/19

N2 - A short and modular synthetic pathway using intramolecular 1,3-dipolar cycloaddition reactions and yielding functionalized isoxazoles, isoxazolines, and isoxazolidines is described. The change in shape of previous compounds and those in this study is quantified and compared using principal moment-of-inertia shape analysis.

AB - A short and modular synthetic pathway using intramolecular 1,3-dipolar cycloaddition reactions and yielding functionalized isoxazoles, isoxazolines, and isoxazolidines is described. The change in shape of previous compounds and those in this study is quantified and compared using principal moment-of-inertia shape analysis.

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Expanding stereochemical and skeletal diversity using petasis reactions and 1,3-dipolar cycloadditions

Abstract

ASJC Scopus subject areas

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