Expression and function of galectin-1 in adult neural stem cells

M. Sakaguchi, Y. Imaizumi, Hideyuki Okano

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Neural stem cells (NSCs) in the adult mammalian brain proliferate and continuously produce new neurons. To date, there has been little research into the functions of lectins in adult NSCs. Recently, we reported that a lectin, galectin-1, is expressed on adult NSCs and promotes their proliferation through its carbohydrate-binding ability. This evidence raises the possibility that glycans play roles in the proliferation of adult NSCs.

Original languageEnglish
Pages (from-to)1254-1258
Number of pages5
JournalCellular and Molecular Life Sciences
Volume64
Issue number10
DOIs
Publication statusPublished - 2007 May

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Keywords

  • Galectin
  • Glycan
  • Lectin
  • Neural stem cell
  • Subventricular zone astrocyte

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Cell Biology

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