Expression patterns of musashi homologs of the ascidians, Halocynthia roretzi and Ciona intestinalis

Takeshi Kawashima, Akikazu R. Murakami, Michio Ogasawara, Kimio J. Tanaka, Ryuji Isoda, Yasunori Sasakura, Takahito Nishikata, Hideyuki Okano, Kazuhiro W. Makabe

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

The gene family encoding RNA-binding proteins includes important regulators involved in the neurogenesis in both protostomes and deuterostomes. We isolated cDNAs of the ascidian homolog of one of the RNA-binding proteins, MUSASHI, from Halocynthia roretzi and Ciona intestinalis. The predicted amino acid sequences contained two RNA-recognition and RNA-binding motifs in the N-terminus and an ascidian-specific YG-rich domain in the C-terminus. Maternal transcripts of musashi were ubiquitous in early cleavage-stage embryos. Ascidian musashi had three domains of zygotic expression: the brain, nerve cord, and mesenchyma. The temporal order of the onset in these domains was highly divergent between the two species of ascidian examined.

Original languageEnglish
Pages (from-to)162-165
Number of pages4
JournalDevelopment Genes and Evolution
Volume210
Issue number3
Publication statusPublished - 2000
Externally publishedYes

Fingerprint

Halocynthia roretzi
Ciona intestinalis
Urochordata
Ascidiacea
RNA
RNA-binding proteins
RNA-Binding Proteins
protein
neurogenesis
Neurogenesis
Mesoderm
cleavage
brain
embryo
Amino Acid Sequence
nerve tissue
embryo (animal)
amino acid sequences
Embryonic Structures
Complementary DNA

Keywords

  • Ascidian
  • Musashi
  • RNA-binding protein

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology
  • Genetics
  • Ecology, Evolution, Behavior and Systematics

Cite this

Kawashima, T., Murakami, A. R., Ogasawara, M., Tanaka, K. J., Isoda, R., Sasakura, Y., ... Makabe, K. W. (2000). Expression patterns of musashi homologs of the ascidians, Halocynthia roretzi and Ciona intestinalis. Development Genes and Evolution, 210(3), 162-165.

Expression patterns of musashi homologs of the ascidians, Halocynthia roretzi and Ciona intestinalis. / Kawashima, Takeshi; Murakami, Akikazu R.; Ogasawara, Michio; Tanaka, Kimio J.; Isoda, Ryuji; Sasakura, Yasunori; Nishikata, Takahito; Okano, Hideyuki; Makabe, Kazuhiro W.

In: Development Genes and Evolution, Vol. 210, No. 3, 2000, p. 162-165.

Research output: Contribution to journalArticle

Kawashima, T, Murakami, AR, Ogasawara, M, Tanaka, KJ, Isoda, R, Sasakura, Y, Nishikata, T, Okano, H & Makabe, KW 2000, 'Expression patterns of musashi homologs of the ascidians, Halocynthia roretzi and Ciona intestinalis', Development Genes and Evolution, vol. 210, no. 3, pp. 162-165.
Kawashima T, Murakami AR, Ogasawara M, Tanaka KJ, Isoda R, Sasakura Y et al. Expression patterns of musashi homologs of the ascidians, Halocynthia roretzi and Ciona intestinalis. Development Genes and Evolution. 2000;210(3):162-165.
Kawashima, Takeshi ; Murakami, Akikazu R. ; Ogasawara, Michio ; Tanaka, Kimio J. ; Isoda, Ryuji ; Sasakura, Yasunori ; Nishikata, Takahito ; Okano, Hideyuki ; Makabe, Kazuhiro W. / Expression patterns of musashi homologs of the ascidians, Halocynthia roretzi and Ciona intestinalis. In: Development Genes and Evolution. 2000 ; Vol. 210, No. 3. pp. 162-165.
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