Extended-nano scale fluidics and applications to bioanalysis

Hisashi Shimizu; Kazuma Mawatari; Yutaka Kazoe; Yuriy Pihosh; Takehiko Kitamori

doi:10.1007/978-4-431-56429-4_5

Extended-nano scale fluidics and applications to bioanalysis

Hisashi Shimizu, Kazuma Mawatari, Yutaka Kazoe, Yuriy Pihosh, Takehiko Kitamori

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Citations (Scopus)

Abstract

Extended-nano space, which is in 10-1000 nm scale, is a transitional region from single molecules to continuous fluid. Even though many specific effects are expected, device engineering of extended-nano space has not been developed so far due to the lack of basic technologies for fluidic engineering. Previously, our group established a strategy of device integration for microchemical systems called continuous flow chemical processing and applied the strategy to various analytical systems. In addition, we have succeeded in developments of basic technologies including fabrication, fluidic control and detection for extended-nano space to find very unique effects such as higher viscosity, lower dielectric constant and higher proton mobility. In this chapter, the uniqueness, device engineering of extended-nano space and its application to bioanalytical devices are introduced. Especially, we focus on an ultimate chromatography using extended-nano space and its innovative performances to break the limits of conventional technologies.

Original language	English
Title of host publication	Intelligent Nanosystems for Energy, Information and Biological Technologies
Publisher	Springer Japan
Pages	65-84
Number of pages	20
ISBN (Electronic)	9784431564294
ISBN (Print)	9784431564270
DOIs	https://doi.org/10.1007/978-4-431-56429-4_5
Publication status	Published - 2016 Jan 1
Externally published	Yes

Keywords

Chromatography
Fuel cell
Immunoassay
Microfluidics
Nanofluidics
Photothermal spectroscopy

ASJC Scopus subject areas

Engineering(all)
Biochemistry, Genetics and Molecular Biology(all)
Medicine(all)
Neuroscience(all)

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Cite this

Shimizu, H., Mawatari, K., Kazoe, Y., Pihosh, Y., & Kitamori, T. (2016). Extended-nano scale fluidics and applications to bioanalysis. In Intelligent Nanosystems for Energy, Information and Biological Technologies (pp. 65-84). Springer Japan. https://doi.org/10.1007/978-4-431-56429-4_5

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abstract = "Extended-nano space, which is in 10-1000 nm scale, is a transitional region from single molecules to continuous fluid. Even though many specific effects are expected, device engineering of extended-nano space has not been developed so far due to the lack of basic technologies for fluidic engineering. Previously, our group established a strategy of device integration for microchemical systems called continuous flow chemical processing and applied the strategy to various analytical systems. In addition, we have succeeded in developments of basic technologies including fabrication, fluidic control and detection for extended-nano space to find very unique effects such as higher viscosity, lower dielectric constant and higher proton mobility. In this chapter, the uniqueness, device engineering of extended-nano space and its application to bioanalytical devices are introduced. Especially, we focus on an ultimate chromatography using extended-nano space and its innovative performances to break the limits of conventional technologies.",

keywords = "Chromatography, Fuel cell, Immunoassay, Microfluidics, Nanofluidics, Photothermal spectroscopy",

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AU - Shimizu, Hisashi

AU - Mawatari, Kazuma

AU - Kazoe, Yutaka

AU - Pihosh, Yuriy

AU - Kitamori, Takehiko

PY - 2016/1/1

Y1 - 2016/1/1

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AB - Extended-nano space, which is in 10-1000 nm scale, is a transitional region from single molecules to continuous fluid. Even though many specific effects are expected, device engineering of extended-nano space has not been developed so far due to the lack of basic technologies for fluidic engineering. Previously, our group established a strategy of device integration for microchemical systems called continuous flow chemical processing and applied the strategy to various analytical systems. In addition, we have succeeded in developments of basic technologies including fabrication, fluidic control and detection for extended-nano space to find very unique effects such as higher viscosity, lower dielectric constant and higher proton mobility. In this chapter, the uniqueness, device engineering of extended-nano space and its application to bioanalytical devices are introduced. Especially, we focus on an ultimate chromatography using extended-nano space and its innovative performances to break the limits of conventional technologies.

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KW - Fuel cell

KW - Immunoassay

KW - Microfluidics

KW - Nanofluidics

KW - Photothermal spectroscopy

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