Extraction of glomeruli in whole slide imaging of kidney biopsy specimens

Masahiro Ishikawa, Sumire Watanabe, Natsuki Honda, Naoki Kobayashi, Tokiya Abe, Akinori Hashiguchi, Michiie Sakamoto

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The pathological diagnosis of a transplanted kidney is made on Banff Classification in order to gain an accurate understanding of the condition of the kidney. This type of diagnosis is extremely difficult and, thus, a variety of methods for diagnosis, including diagnosis by electron microscope, are being considered at present. Quantification of the diagnostic information derived by image processing is required for such purposes. This study proposes an automatic extraction method for normal glomeruli for the purpose of quantifying Elastica Van Gieson(EVG)-stained pathology specimens. In addition, we provide a report on the package of methods that we have created for the extraction of the glomerulus in the cortex.

Original languageEnglish
Title of host publicationMedical Imaging 2017
Subtitle of host publicationDigital Pathology
ISBN (Electronic)9781510607255
Publication statusPublished - 2017
EventMedical Imaging 2017: Digital Pathology - Orlando, United States
Duration: 2017 Feb 122017 Feb 13


OtherMedical Imaging 2017: Digital Pathology
CountryUnited States


  • Extraction of glomerulus
  • Histopathological tissue images
  • Whole slide imaging

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Ishikawa, M., Watanabe, S., Honda, N., Kobayashi, N., Abe, T., Hashiguchi, A., & Sakamoto, M. (2017). Extraction of glomeruli in whole slide imaging of kidney biopsy specimens. In Medical Imaging 2017: Digital Pathology (Vol. 10140). [101400U] SPIE. https://doi.org/10.1117/12.2254306