Extramedullary myeloid tumour (EMMT) of the gallbladder

H. Ojima, T. Hasegawa, Y. Matsuno, M. Sakamoto

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

This report describes a rare case of an extramedullary myeloid tumour (EMMT) of the gallbladder in a patient without leukaemia. A 33 year old man visited a local hospital because of jaundice. Abdominal computed tomography revealed a tumorous mass measuring 6.0 × 4.5 cm and involving the entire gallbladder. A percutaneous needle biopsy was attempted, but because adenocarcinoma could not be completely ruled out, the use of undue force was considered dangerous. Under a preoperative diagnosis of gallbladder carcinoma, a hepatopancreatoduodenectomy was performed. The tumour cells exhibited various amounts of eosinophilic cytoplasm, had medium sized round nuclei with indentation and grooving, and were strongly immunoreactive for myeloperoxidase, CD43, and c-kit protein (CD117). After surgery, the patient underwent combination chemotherapy as prescribed for cases of acute myeloblastic leukaemia. The patient did not develop acute leukaemia during a follow up period of four years. In conclusion, a correct diagnosis of EMMT can be made using appropriate immunohistochemical staining.

Original languageEnglish
Pages (from-to)211-213
Number of pages3
JournalJournal of Clinical Pathology
Volume58
Issue number2
DOIs
Publication statusPublished - 2005 Feb

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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