Extraosseous accumulation of 99mTc phosphonate complexes in primary brain tumor evaluated with SPECT

Aya Suzuki, Takashi Togawa, Junpei Kuyama, Tadaki Nakahara, Nobuharu Yui, Toshihiko Iuchi, Masaru Oga, Katsunobu Osato

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Although extraosseous accumulations of 99mTc phosphate complexes are phenomena which can often be seen, no case showing extraosseous accumulation to brain tumor on SPECT has been reported. We report here two cases of primary brain tumor showing extraosseous accumulation of 99mTc phosphate in bone SPECT. 201TI SPECT also showed increased 201TI uptake by the tumor. Comparing bone SPECT with 201TI SPECT, the regions of abnormality of both SPECTs were very similar in the case of glioblastoma, but in the case of malignant lymphoma the region showing intense uptake of 99mTc-MDP was smaller than that on 201TI SPECT. It was revealed that bone SPECT is more useful in the assessment of extraosseous accumulation to a primary brain tumor than conventional bone scintigraphy.

Original languageEnglish
Pages (from-to)495-498
Number of pages4
JournalAnnals of Nuclear Medicine
Issue number7
Publication statusPublished - 2002 Nov
Externally publishedYes


  • Bone SPECT
  • Extraosseous accumulation
  • Primary brain tumor

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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