TY - JOUR
T1 - Factors affecting heart rate as measured at home among treated hypertensive patients
T2 - The Japan home versus office blood pressure measurement evaluation (J-HOME) study
AU - Komai, Rie
AU - Obara, Taku
AU - Ohkubo, Takayoshi
AU - Kato, Tetsuo
AU - Kikuya, Masahiro
AU - Metoki, Hirohito
AU - Inoue, Ryusuke
AU - Asayama, Kei
AU - Hara, Azusa
AU - Tanaka, Koji
AU - Gonokami, Kenta
AU - Hashimoto, Junichiro
AU - Totsune, Kazuhito
AU - Imai, Yutaka
AU - Fujishima, Masatoshi
AU - Saruta, Takao
AU - Ogihara, Toshio
AU - Shimamoto, Kazuaki
AU - Fujita, Toshiro
AU - Shimada, Kazuyuki
AU - Ikeda, Toshio
AU - Kuwajima, Iwao
AU - Kuriyama, Satoru
AU - Kario, Kazuomi
AU - Oikawa, Takuya
AU - Murai, Kayo
AU - Horikawa, Tsuyoshi
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2007/11
Y1 - 2007/11
N2 - We previously reported that a resting heart rate measured at home (home HR) of ≥70 beats per minute was a powerful predictor of the risk of cardiovascular disease mortality, and identified factors affecting home HR in the general Japanese population. The present study examines factors affecting home HR in hypertensive patients treated with antihypertensive medications. Home HR was measured using a home blood pressure (BP) device. Information about the characteristics of the patients was collected using questionnaires administered by a physician. Among 3,400 patients, 3,086 measured home HR both in the morning and evening. The mean values of home HR in the morning and evening were 67.2±9.1 and 69.6±9.2 beats per minute, respectively. Multivariate linear regression analysis showed that lower age, diabetes mellitus, habitual smoking, higher diastolic BP, and the lack of β-blocker or angiotensin-converting enzyme inhibitor use were determinants of elevated morning or evening home HR. These results suggest that adequate control of risk factors for cardiovascular disease such as smoking and diabetes mellitus or use of heart rate-lowering agents might help to decrease home HR in treated hypertensive patients.
AB - We previously reported that a resting heart rate measured at home (home HR) of ≥70 beats per minute was a powerful predictor of the risk of cardiovascular disease mortality, and identified factors affecting home HR in the general Japanese population. The present study examines factors affecting home HR in hypertensive patients treated with antihypertensive medications. Home HR was measured using a home blood pressure (BP) device. Information about the characteristics of the patients was collected using questionnaires administered by a physician. Among 3,400 patients, 3,086 measured home HR both in the morning and evening. The mean values of home HR in the morning and evening were 67.2±9.1 and 69.6±9.2 beats per minute, respectively. Multivariate linear regression analysis showed that lower age, diabetes mellitus, habitual smoking, higher diastolic BP, and the lack of β-blocker or angiotensin-converting enzyme inhibitor use were determinants of elevated morning or evening home HR. These results suggest that adequate control of risk factors for cardiovascular disease such as smoking and diabetes mellitus or use of heart rate-lowering agents might help to decrease home HR in treated hypertensive patients.
KW - Home heart rate
KW - Life-style modifications
KW - β-blockers
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U2 - 10.1291/hypres.30.1051
DO - 10.1291/hypres.30.1051
M3 - Article
C2 - 18250554
AN - SCOPUS:37849022126
SN - 0916-9636
VL - 30
SP - 1051
EP - 1057
JO - Hypertension Research
JF - Hypertension Research
IS - 11
ER -
