Fast spin-echo MR in the detection of vertebral metastases: Comparison of three sequences

K. M. Jones, R. B. Schwartz, M. T. Mantello, S. S. Ahn, R. Khorasani, S. Mukherji, Koichi Oshio, R. V. Mulkern

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

PURPOSE: To examine the relative capabilities for the detection of vertebral metastases of three available fast spin-echo sequences: T1-weighted fast spin-echo, short tau inversion recovery (STIR) fast spin-echo, and T2- weighted fast spin-echo sequences with chemical shift selective saturation pulse fat suppression. METHODS: Fourteen patients were evaluated prospectively over a 2-month period with T1-weighted fast spin-echo (four echo train, four acquisitions, 1 min 59 sec-2 min 37 sec), STIR fast spin- echo (16 echo train, four acquisitions, 2 min 30 sec-3 min 19 sec), and T2- weighted fast spin-echo (16 echo train, 4 acquisitions, 2 min 27 sec-3 min 16 sec). For all three pulse sequences, measurements were obtained of the signal intensities of normal marrow, abnormal marrow, fat, and noise posterior to the spine. Contrast-to-noise ratios were calculated for metastases in each case. Lesions were evaluated by three observers and rated for size, location, and conspicuity. RESULTS: Signal intensities of fat, normal marrow, and noise were highest for T1-weighted fast spin-echo sequences. STIR fast spin-echo and fat-suppressed T2-weighted fast spin-echo had approximately similar fat- suppression capabilities. Though contrast-to-noise ratios were highest overall for STIR fast spin-echo, the finding was not statistically significant and lesion conspicuity was deemed better with fat-suppressed T2- weighted fast spin-echo and T1-weighted fast spin-echo images. Discrete lesions were well identified on all three pulse sequences. CONCLUSION: Fast spin-echo sequences appear promising for the detection of vertebral metastases. Further work should be directed toward comparison with conventional spin-echo to determine whether fast spin-echo may replace conventional spin-echo sequences for evaluation of vertebral metastases.

Original languageEnglish
Pages (from-to)401-407
Number of pages7
JournalAmerican Journal of Neuroradiology
Volume15
Issue number3
Publication statusPublished - 1994
Externally publishedYes

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Fats
Neoplasm Metastasis
Noise
Bone Marrow
Spine

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Jones, K. M., Schwartz, R. B., Mantello, M. T., Ahn, S. S., Khorasani, R., Mukherji, S., ... Mulkern, R. V. (1994). Fast spin-echo MR in the detection of vertebral metastases: Comparison of three sequences. American Journal of Neuroradiology, 15(3), 401-407.

Fast spin-echo MR in the detection of vertebral metastases : Comparison of three sequences. / Jones, K. M.; Schwartz, R. B.; Mantello, M. T.; Ahn, S. S.; Khorasani, R.; Mukherji, S.; Oshio, Koichi; Mulkern, R. V.

In: American Journal of Neuroradiology, Vol. 15, No. 3, 1994, p. 401-407.

Research output: Contribution to journalArticle

Jones, KM, Schwartz, RB, Mantello, MT, Ahn, SS, Khorasani, R, Mukherji, S, Oshio, K & Mulkern, RV 1994, 'Fast spin-echo MR in the detection of vertebral metastases: Comparison of three sequences', American Journal of Neuroradiology, vol. 15, no. 3, pp. 401-407.
Jones KM, Schwartz RB, Mantello MT, Ahn SS, Khorasani R, Mukherji S et al. Fast spin-echo MR in the detection of vertebral metastases: Comparison of three sequences. American Journal of Neuroradiology. 1994;15(3):401-407.
Jones, K. M. ; Schwartz, R. B. ; Mantello, M. T. ; Ahn, S. S. ; Khorasani, R. ; Mukherji, S. ; Oshio, Koichi ; Mulkern, R. V. / Fast spin-echo MR in the detection of vertebral metastases : Comparison of three sequences. In: American Journal of Neuroradiology. 1994 ; Vol. 15, No. 3. pp. 401-407.
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abstract = "PURPOSE: To examine the relative capabilities for the detection of vertebral metastases of three available fast spin-echo sequences: T1-weighted fast spin-echo, short tau inversion recovery (STIR) fast spin-echo, and T2- weighted fast spin-echo sequences with chemical shift selective saturation pulse fat suppression. METHODS: Fourteen patients were evaluated prospectively over a 2-month period with T1-weighted fast spin-echo (four echo train, four acquisitions, 1 min 59 sec-2 min 37 sec), STIR fast spin- echo (16 echo train, four acquisitions, 2 min 30 sec-3 min 19 sec), and T2- weighted fast spin-echo (16 echo train, 4 acquisitions, 2 min 27 sec-3 min 16 sec). For all three pulse sequences, measurements were obtained of the signal intensities of normal marrow, abnormal marrow, fat, and noise posterior to the spine. Contrast-to-noise ratios were calculated for metastases in each case. Lesions were evaluated by three observers and rated for size, location, and conspicuity. RESULTS: Signal intensities of fat, normal marrow, and noise were highest for T1-weighted fast spin-echo sequences. STIR fast spin-echo and fat-suppressed T2-weighted fast spin-echo had approximately similar fat- suppression capabilities. Though contrast-to-noise ratios were highest overall for STIR fast spin-echo, the finding was not statistically significant and lesion conspicuity was deemed better with fat-suppressed T2- weighted fast spin-echo and T1-weighted fast spin-echo images. Discrete lesions were well identified on all three pulse sequences. CONCLUSION: Fast spin-echo sequences appear promising for the detection of vertebral metastases. Further work should be directed toward comparison with conventional spin-echo to determine whether fast spin-echo may replace conventional spin-echo sequences for evaluation of vertebral metastases.",
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AU - Jones, K. M.

AU - Schwartz, R. B.

AU - Mantello, M. T.

AU - Ahn, S. S.

AU - Khorasani, R.

AU - Mukherji, S.

AU - Oshio, Koichi

AU - Mulkern, R. V.

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N2 - PURPOSE: To examine the relative capabilities for the detection of vertebral metastases of three available fast spin-echo sequences: T1-weighted fast spin-echo, short tau inversion recovery (STIR) fast spin-echo, and T2- weighted fast spin-echo sequences with chemical shift selective saturation pulse fat suppression. METHODS: Fourteen patients were evaluated prospectively over a 2-month period with T1-weighted fast spin-echo (four echo train, four acquisitions, 1 min 59 sec-2 min 37 sec), STIR fast spin- echo (16 echo train, four acquisitions, 2 min 30 sec-3 min 19 sec), and T2- weighted fast spin-echo (16 echo train, 4 acquisitions, 2 min 27 sec-3 min 16 sec). For all three pulse sequences, measurements were obtained of the signal intensities of normal marrow, abnormal marrow, fat, and noise posterior to the spine. Contrast-to-noise ratios were calculated for metastases in each case. Lesions were evaluated by three observers and rated for size, location, and conspicuity. RESULTS: Signal intensities of fat, normal marrow, and noise were highest for T1-weighted fast spin-echo sequences. STIR fast spin-echo and fat-suppressed T2-weighted fast spin-echo had approximately similar fat- suppression capabilities. Though contrast-to-noise ratios were highest overall for STIR fast spin-echo, the finding was not statistically significant and lesion conspicuity was deemed better with fat-suppressed T2- weighted fast spin-echo and T1-weighted fast spin-echo images. Discrete lesions were well identified on all three pulse sequences. CONCLUSION: Fast spin-echo sequences appear promising for the detection of vertebral metastases. Further work should be directed toward comparison with conventional spin-echo to determine whether fast spin-echo may replace conventional spin-echo sequences for evaluation of vertebral metastases.

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