Fasting plasma insulin is associated with metabolic syndrome in farmers but not in nomads among the Mongolian population, China.

Hideyuki Kanda, Peiyu Wang, Tomonori Okamura, GaoWa Wuyun, HePing Wu, Xiulan Su, Takehito Hayakawa, Kenji Amamoto, Hirotsugu Ueshima

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The World Health Organization (WHO) includes insulin resistance among its criteria for diagnosing metabolic syndrome (MetS); however, previous epidemiologic studies have limited their research to settled populations only. This study aims to clarify the relationship between plasma insulin and metabolic factors on a broader scale by studying data obtained from nomadic and settled Mongolian populations. A cross-sectional epidemiologic study of 200 nomads and 256 farmers was performed in Inner Mongolia, Republic of China. Plasma insulin levels and other metabolic factors, such as blood pressure, serum lipids and obesity, were measured. Participants were classified into 3 categories according to their plasma insulin levels. Cut-off values grouped into tertiles of fasting insulin for all participants were 6.73 nmol/L and 10.33 nmol/L. The mean number of metabolic risk factors, waist circumference, fasting plasma glucose and triglyceride were higher, and the mean HDL cholesterol was lower in the higher fasting insulin tertile among farmers after adjusting for age, gender, smoking, alcohol drinking and total cholesterol. However, no MetS factors were statistically related with fasting insulin tertile levels among nomads. In nomads, hyperinsulinemia may not be an indicator of MetS due to their specific life-style.

Original languageEnglish
Pages (from-to)291-297
Number of pages7
JournalJournal of Atherosclerosis and Thrombosis
Volume18
Issue number4
DOIs
Publication statusPublished - 2011 Apr 27
Externally publishedYes

Fingerprint

Fasting
China
Insulin
Plasmas
Population
Epidemiologic Studies
Hyperinsulinism
Waist Circumference
Taiwan
Alcohol Drinking
Blood pressure
HDL Cholesterol
Insulin Resistance
Hyperthermia, Cutaneous, With Headaches And Nausea
Life Style
Triglycerides
Obesity
Cross-Sectional Studies
Smoking
Cholesterol

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Internal Medicine
  • Biochemistry, medical

Cite this

Fasting plasma insulin is associated with metabolic syndrome in farmers but not in nomads among the Mongolian population, China. / Kanda, Hideyuki; Wang, Peiyu; Okamura, Tomonori; Wuyun, GaoWa; Wu, HePing; Su, Xiulan; Hayakawa, Takehito; Amamoto, Kenji; Ueshima, Hirotsugu.

In: Journal of Atherosclerosis and Thrombosis, Vol. 18, No. 4, 27.04.2011, p. 291-297.

Research output: Contribution to journalArticle

Kanda, Hideyuki ; Wang, Peiyu ; Okamura, Tomonori ; Wuyun, GaoWa ; Wu, HePing ; Su, Xiulan ; Hayakawa, Takehito ; Amamoto, Kenji ; Ueshima, Hirotsugu. / Fasting plasma insulin is associated with metabolic syndrome in farmers but not in nomads among the Mongolian population, China. In: Journal of Atherosclerosis and Thrombosis. 2011 ; Vol. 18, No. 4. pp. 291-297.
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