Feasibility of CT-guided large-bore biopsy of lung tumors with the use of an outer sheath

Yotaro Izumi, Seishi Nakatsuka, Keisuke Asakura, Kenzo Soejima, Hiroaki Nomori

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose: To evaluate the feasibility, volume of biopsy specimens, and procedure-related tumor seeding of computed tomography (CT)guided large-bore lung tumor biopsy through an outer sheath in advanced lung cancer. Materials and Methods: Eighteen procedures were performed in 18 patients with established diagnosis of advanced or recurrent lung cancer. Biopsy specimens were obtained under local anesthesia and with fluoroscopic CT guidance. First, an outer sheath was placed in the tumor. Next, a semiautomatic cutting biopsy needle (14-gauge, n = 6; 12-gauge, n = 12) was inserted through the outer sheath, and the tumor biopsy specimen was obtained. After biopsy, the outer sheath was left in place for approximately 10 minutes, during which time hemostasis was achieved. The primary goal was feasibility. Secondary goals were volume of biopsy specimens and incidence of procedure-related tumor implantation. Results: Bleeding volume during the procedure ranged from 050 g (median, 5 g; mean, 9 g) and stopped within 10 minutes in all patients. Pneumothorax occurred in two patients (11 %) and improved without chest tube insertion. Specimens could be obtained for the full needle length (2 cm) in 17 patients (94%), which enabled the chemosensitivity test to be performed in 14 patients (78%). Procedure-related tumor seeding was not apparent in any patient at a median of 16 months of follow-up after the procedure. Conclusions: The present study showed that lung tumor biopsy with a 12-gauge needle through an outer sheath was feasible and enabled acquisition of specimens adequate for chemosensitivity testing without apparent procedure-related tumor seeding.

Original languageEnglish
Pages (from-to)699-701
Number of pages3
JournalJournal of Vascular and Interventional Radiology
Volume22
Issue number5
DOIs
Publication statusPublished - 2011 May

Fingerprint

Tomography
Biopsy
Lung
Neoplasms
Needles
Lung Neoplasms
Chest Tubes
Needle Biopsy
Pneumothorax
Local Anesthesia
Hemostasis
Hemorrhage
Incidence

Keywords

  • CD-DST
  • collagen gel droplet embedded culture drug sensitivity test

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Feasibility of CT-guided large-bore biopsy of lung tumors with the use of an outer sheath. / Izumi, Yotaro; Nakatsuka, Seishi; Asakura, Keisuke; Soejima, Kenzo; Nomori, Hiroaki.

In: Journal of Vascular and Interventional Radiology, Vol. 22, No. 5, 05.2011, p. 699-701.

Research output: Contribution to journalArticle

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