Feasibility of endoscopic submucosal dissection for patients with chronic renal failure on hemodialysis

Osamu Goto, Mitsuhiro Fujishiro, Shinya Kodashima, Satoshi Ono, Keiko Niimi, Nobutake Yamamichi, Masao Omata

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background: Endoscopic submucosal dissection (ESD) is expected as a curative method for node-negative gastrointestinal cancers. Little is known about ESD for patients with end-stage chronic renal failure (CRF) on hemodialysis. We aimed to evaluate the efficacy and safety of ESD for patients with CRF on hemodialysis. Methods: Ten consecutive patients with 12 lesions who underwent ESD (stomach, seven; colorectum, three) between March 2002 and August 2007 were retrospectively investigated in terms of the technical feasibility and complications. Results: All the lesions were resected in a single piece and en-bloc and R0 resection rate was 100%. Histology revealed that all the lesions fulfilled the criteria of node-negative cancers. Delayed bleeding requiring blood transfusion on the day after ESD, and shunt occlusion, which necessitated a radiological intervention 7 days after ESD, occurred in one stomach case. Delayed perforation followed by emergency surgery 2 days after ESD occurred in one colorectal case. Conclusions: ESD for CRF patients may be technically feasible, but substantial risks should be considered. Early detection of late-onset complications is essential with intensive medical check-up for at least 1 week in order to prevent complications from becoming severe.

Original languageEnglish
Pages (from-to)45-48
Number of pages4
JournalDigestive Endoscopy
Volume22
Issue number1
DOIs
Publication statusPublished - 2010 Jan
Externally publishedYes

Fingerprint

Chronic Kidney Failure
Renal Dialysis
Stomach
Gastrointestinal Neoplasms
Endoscopic Mucosal Resection
Ambulatory Surgical Procedures
Blood Transfusion
Histology
Emergencies
Hemorrhage
Safety
Neoplasms

Keywords

  • Chronic renal failure
  • Endoscopic submucosal dissection
  • Gastrointestinal cancers
  • Hemodialysis

ASJC Scopus subject areas

  • Gastroenterology
  • Radiology Nuclear Medicine and imaging

Cite this

Feasibility of endoscopic submucosal dissection for patients with chronic renal failure on hemodialysis. / Goto, Osamu; Fujishiro, Mitsuhiro; Kodashima, Shinya; Ono, Satoshi; Niimi, Keiko; Yamamichi, Nobutake; Omata, Masao.

In: Digestive Endoscopy, Vol. 22, No. 1, 01.2010, p. 45-48.

Research output: Contribution to journalArticle

Goto, O, Fujishiro, M, Kodashima, S, Ono, S, Niimi, K, Yamamichi, N & Omata, M 2010, 'Feasibility of endoscopic submucosal dissection for patients with chronic renal failure on hemodialysis', Digestive Endoscopy, vol. 22, no. 1, pp. 45-48. https://doi.org/10.1111/j.1443-1661.2009.00927.x
Goto, Osamu ; Fujishiro, Mitsuhiro ; Kodashima, Shinya ; Ono, Satoshi ; Niimi, Keiko ; Yamamichi, Nobutake ; Omata, Masao. / Feasibility of endoscopic submucosal dissection for patients with chronic renal failure on hemodialysis. In: Digestive Endoscopy. 2010 ; Vol. 22, No. 1. pp. 45-48.
@article{5eff51f22d6946e6a85c490ca92d7075,
title = "Feasibility of endoscopic submucosal dissection for patients with chronic renal failure on hemodialysis",
abstract = "Background: Endoscopic submucosal dissection (ESD) is expected as a curative method for node-negative gastrointestinal cancers. Little is known about ESD for patients with end-stage chronic renal failure (CRF) on hemodialysis. We aimed to evaluate the efficacy and safety of ESD for patients with CRF on hemodialysis. Methods: Ten consecutive patients with 12 lesions who underwent ESD (stomach, seven; colorectum, three) between March 2002 and August 2007 were retrospectively investigated in terms of the technical feasibility and complications. Results: All the lesions were resected in a single piece and en-bloc and R0 resection rate was 100{\%}. Histology revealed that all the lesions fulfilled the criteria of node-negative cancers. Delayed bleeding requiring blood transfusion on the day after ESD, and shunt occlusion, which necessitated a radiological intervention 7 days after ESD, occurred in one stomach case. Delayed perforation followed by emergency surgery 2 days after ESD occurred in one colorectal case. Conclusions: ESD for CRF patients may be technically feasible, but substantial risks should be considered. Early detection of late-onset complications is essential with intensive medical check-up for at least 1 week in order to prevent complications from becoming severe.",
keywords = "Chronic renal failure, Endoscopic submucosal dissection, Gastrointestinal cancers, Hemodialysis",
author = "Osamu Goto and Mitsuhiro Fujishiro and Shinya Kodashima and Satoshi Ono and Keiko Niimi and Nobutake Yamamichi and Masao Omata",
year = "2010",
month = "1",
doi = "10.1111/j.1443-1661.2009.00927.x",
language = "English",
volume = "22",
pages = "45--48",
journal = "Digestive Endoscopy",
issn = "0915-5635",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Feasibility of endoscopic submucosal dissection for patients with chronic renal failure on hemodialysis

AU - Goto, Osamu

AU - Fujishiro, Mitsuhiro

AU - Kodashima, Shinya

AU - Ono, Satoshi

AU - Niimi, Keiko

AU - Yamamichi, Nobutake

AU - Omata, Masao

PY - 2010/1

Y1 - 2010/1

N2 - Background: Endoscopic submucosal dissection (ESD) is expected as a curative method for node-negative gastrointestinal cancers. Little is known about ESD for patients with end-stage chronic renal failure (CRF) on hemodialysis. We aimed to evaluate the efficacy and safety of ESD for patients with CRF on hemodialysis. Methods: Ten consecutive patients with 12 lesions who underwent ESD (stomach, seven; colorectum, three) between March 2002 and August 2007 were retrospectively investigated in terms of the technical feasibility and complications. Results: All the lesions were resected in a single piece and en-bloc and R0 resection rate was 100%. Histology revealed that all the lesions fulfilled the criteria of node-negative cancers. Delayed bleeding requiring blood transfusion on the day after ESD, and shunt occlusion, which necessitated a radiological intervention 7 days after ESD, occurred in one stomach case. Delayed perforation followed by emergency surgery 2 days after ESD occurred in one colorectal case. Conclusions: ESD for CRF patients may be technically feasible, but substantial risks should be considered. Early detection of late-onset complications is essential with intensive medical check-up for at least 1 week in order to prevent complications from becoming severe.

AB - Background: Endoscopic submucosal dissection (ESD) is expected as a curative method for node-negative gastrointestinal cancers. Little is known about ESD for patients with end-stage chronic renal failure (CRF) on hemodialysis. We aimed to evaluate the efficacy and safety of ESD for patients with CRF on hemodialysis. Methods: Ten consecutive patients with 12 lesions who underwent ESD (stomach, seven; colorectum, three) between March 2002 and August 2007 were retrospectively investigated in terms of the technical feasibility and complications. Results: All the lesions were resected in a single piece and en-bloc and R0 resection rate was 100%. Histology revealed that all the lesions fulfilled the criteria of node-negative cancers. Delayed bleeding requiring blood transfusion on the day after ESD, and shunt occlusion, which necessitated a radiological intervention 7 days after ESD, occurred in one stomach case. Delayed perforation followed by emergency surgery 2 days after ESD occurred in one colorectal case. Conclusions: ESD for CRF patients may be technically feasible, but substantial risks should be considered. Early detection of late-onset complications is essential with intensive medical check-up for at least 1 week in order to prevent complications from becoming severe.

KW - Chronic renal failure

KW - Endoscopic submucosal dissection

KW - Gastrointestinal cancers

KW - Hemodialysis

UR - http://www.scopus.com/inward/record.url?scp=74049096253&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=74049096253&partnerID=8YFLogxK

U2 - 10.1111/j.1443-1661.2009.00927.x

DO - 10.1111/j.1443-1661.2009.00927.x

M3 - Article

VL - 22

SP - 45

EP - 48

JO - Digestive Endoscopy

JF - Digestive Endoscopy

SN - 0915-5635

IS - 1

ER -