Feasibility of stomach exploration with a guided capsule endoscope

J. F. Rey, Haruhiko Ogata, Naoki Hosoe, K. Ohtsuka, N. Ogata, K. Ikeda, H. Aihara, I. Pangtay, T. Hibi, S. Kudo, H. Tajiri

Research output: Contribution to journalArticle

105 Citations (Scopus)

Abstract

Background and study aims: Video capsule endoscopy has been established in diagnosis of small-bowel disease and has been evaluated for esophageal pathology and recently for colorectal diagnostics. Gastric capsule endoscopy has not hitherto been feasible due to the stomachs large surface area and volume. We present the first application of a magnetically navigated capsule in the human stomach. Patients and methods: 29 volunteers and 24 patients (men 42, women 11; mean age 47.5 years) were included in a feasibility study. Low-level magnetic fields were used to maneuver the double-sensor video capsule within the human stomach with an air-water interface provided by ingestion of 1300ml water within 1 hour before examination. Visualization of all parts of the stomach was attempted; time for visualization was recorded, and a subjective assessment of completeness of visualization was documented. Results: There was technical failure in one individual; thus technical success rate was 98%. In the 52 remaining cases, examiners assessed that the antrum, body, fundus, and cardia were fully visualized in 98%, 96%, 73% and 75%, respectively. Mean duration of examinations was 30 minutes (range 850), with a longer time (mean 37 minutes) for volunteers for study reasons. In total, 30 findings were identified: 14 were detected by both gastroscopy and capsule, 10 lesions were identified by guided capsule examination only, 6 by gastroscopy only. No significant capsule-related adverse events occurred. Conclusion: Magnetically navigated video capsule endoscopy appears to be feasible and sufficiently accurate for gastric examination. It may permit endoscopic examinations that are more patient-friendly and without sedation. Comparative studies are under way.

Original languageEnglish
Pages (from-to)541-545
Number of pages5
JournalEndoscopy
Volume42
Issue number7
DOIs
Publication statusPublished - 2010

Fingerprint

Capsule Endoscopes
Stomach
Capsules
Capsule Endoscopy
Gastroscopy
Volunteers
Cardia
Water
Feasibility Studies
Magnetic Fields
Eating
Air
Pathology

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Rey, J. F., Ogata, H., Hosoe, N., Ohtsuka, K., Ogata, N., Ikeda, K., ... Tajiri, H. (2010). Feasibility of stomach exploration with a guided capsule endoscope. Endoscopy, 42(7), 541-545. https://doi.org/10.1055/s-0030-1255521

Feasibility of stomach exploration with a guided capsule endoscope. / Rey, J. F.; Ogata, Haruhiko; Hosoe, Naoki; Ohtsuka, K.; Ogata, N.; Ikeda, K.; Aihara, H.; Pangtay, I.; Hibi, T.; Kudo, S.; Tajiri, H.

In: Endoscopy, Vol. 42, No. 7, 2010, p. 541-545.

Research output: Contribution to journalArticle

Rey, JF, Ogata, H, Hosoe, N, Ohtsuka, K, Ogata, N, Ikeda, K, Aihara, H, Pangtay, I, Hibi, T, Kudo, S & Tajiri, H 2010, 'Feasibility of stomach exploration with a guided capsule endoscope', Endoscopy, vol. 42, no. 7, pp. 541-545. https://doi.org/10.1055/s-0030-1255521
Rey, J. F. ; Ogata, Haruhiko ; Hosoe, Naoki ; Ohtsuka, K. ; Ogata, N. ; Ikeda, K. ; Aihara, H. ; Pangtay, I. ; Hibi, T. ; Kudo, S. ; Tajiri, H. / Feasibility of stomach exploration with a guided capsule endoscope. In: Endoscopy. 2010 ; Vol. 42, No. 7. pp. 541-545.
@article{ab7e3b822ff14099996c253d98b7c2c5,
title = "Feasibility of stomach exploration with a guided capsule endoscope",
abstract = "Background and study aims: Video capsule endoscopy has been established in diagnosis of small-bowel disease and has been evaluated for esophageal pathology and recently for colorectal diagnostics. Gastric capsule endoscopy has not hitherto been feasible due to the stomachs large surface area and volume. We present the first application of a magnetically navigated capsule in the human stomach. Patients and methods: 29 volunteers and 24 patients (men 42, women 11; mean age 47.5 years) were included in a feasibility study. Low-level magnetic fields were used to maneuver the double-sensor video capsule within the human stomach with an air-water interface provided by ingestion of 1300ml water within 1 hour before examination. Visualization of all parts of the stomach was attempted; time for visualization was recorded, and a subjective assessment of completeness of visualization was documented. Results: There was technical failure in one individual; thus technical success rate was 98{\%}. In the 52 remaining cases, examiners assessed that the antrum, body, fundus, and cardia were fully visualized in 98{\%}, 96{\%}, 73{\%} and 75{\%}, respectively. Mean duration of examinations was 30 minutes (range 850), with a longer time (mean 37 minutes) for volunteers for study reasons. In total, 30 findings were identified: 14 were detected by both gastroscopy and capsule, 10 lesions were identified by guided capsule examination only, 6 by gastroscopy only. No significant capsule-related adverse events occurred. Conclusion: Magnetically navigated video capsule endoscopy appears to be feasible and sufficiently accurate for gastric examination. It may permit endoscopic examinations that are more patient-friendly and without sedation. Comparative studies are under way.",
author = "Rey, {J. F.} and Haruhiko Ogata and Naoki Hosoe and K. Ohtsuka and N. Ogata and K. Ikeda and H. Aihara and I. Pangtay and T. Hibi and S. Kudo and H. Tajiri",
year = "2010",
doi = "10.1055/s-0030-1255521",
language = "English",
volume = "42",
pages = "541--545",
journal = "Endoscopy",
issn = "0013-726X",
publisher = "Georg Thieme Verlag",
number = "7",

}

TY - JOUR

T1 - Feasibility of stomach exploration with a guided capsule endoscope

AU - Rey, J. F.

AU - Ogata, Haruhiko

AU - Hosoe, Naoki

AU - Ohtsuka, K.

AU - Ogata, N.

AU - Ikeda, K.

AU - Aihara, H.

AU - Pangtay, I.

AU - Hibi, T.

AU - Kudo, S.

AU - Tajiri, H.

PY - 2010

Y1 - 2010

N2 - Background and study aims: Video capsule endoscopy has been established in diagnosis of small-bowel disease and has been evaluated for esophageal pathology and recently for colorectal diagnostics. Gastric capsule endoscopy has not hitherto been feasible due to the stomachs large surface area and volume. We present the first application of a magnetically navigated capsule in the human stomach. Patients and methods: 29 volunteers and 24 patients (men 42, women 11; mean age 47.5 years) were included in a feasibility study. Low-level magnetic fields were used to maneuver the double-sensor video capsule within the human stomach with an air-water interface provided by ingestion of 1300ml water within 1 hour before examination. Visualization of all parts of the stomach was attempted; time for visualization was recorded, and a subjective assessment of completeness of visualization was documented. Results: There was technical failure in one individual; thus technical success rate was 98%. In the 52 remaining cases, examiners assessed that the antrum, body, fundus, and cardia were fully visualized in 98%, 96%, 73% and 75%, respectively. Mean duration of examinations was 30 minutes (range 850), with a longer time (mean 37 minutes) for volunteers for study reasons. In total, 30 findings were identified: 14 were detected by both gastroscopy and capsule, 10 lesions were identified by guided capsule examination only, 6 by gastroscopy only. No significant capsule-related adverse events occurred. Conclusion: Magnetically navigated video capsule endoscopy appears to be feasible and sufficiently accurate for gastric examination. It may permit endoscopic examinations that are more patient-friendly and without sedation. Comparative studies are under way.

AB - Background and study aims: Video capsule endoscopy has been established in diagnosis of small-bowel disease and has been evaluated for esophageal pathology and recently for colorectal diagnostics. Gastric capsule endoscopy has not hitherto been feasible due to the stomachs large surface area and volume. We present the first application of a magnetically navigated capsule in the human stomach. Patients and methods: 29 volunteers and 24 patients (men 42, women 11; mean age 47.5 years) were included in a feasibility study. Low-level magnetic fields were used to maneuver the double-sensor video capsule within the human stomach with an air-water interface provided by ingestion of 1300ml water within 1 hour before examination. Visualization of all parts of the stomach was attempted; time for visualization was recorded, and a subjective assessment of completeness of visualization was documented. Results: There was technical failure in one individual; thus technical success rate was 98%. In the 52 remaining cases, examiners assessed that the antrum, body, fundus, and cardia were fully visualized in 98%, 96%, 73% and 75%, respectively. Mean duration of examinations was 30 minutes (range 850), with a longer time (mean 37 minutes) for volunteers for study reasons. In total, 30 findings were identified: 14 were detected by both gastroscopy and capsule, 10 lesions were identified by guided capsule examination only, 6 by gastroscopy only. No significant capsule-related adverse events occurred. Conclusion: Magnetically navigated video capsule endoscopy appears to be feasible and sufficiently accurate for gastric examination. It may permit endoscopic examinations that are more patient-friendly and without sedation. Comparative studies are under way.

UR - http://www.scopus.com/inward/record.url?scp=77954260926&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77954260926&partnerID=8YFLogxK

U2 - 10.1055/s-0030-1255521

DO - 10.1055/s-0030-1255521

M3 - Article

C2 - 20593331

AN - SCOPUS:77954260926

VL - 42

SP - 541

EP - 545

JO - Endoscopy

JF - Endoscopy

SN - 0013-726X

IS - 7

ER -