Fiber-optic conical microsensors for surface plasmon resonance using chemically etched single-mode fiber

Kazuyoshi Kurihara, Hiroyuki Ohkawa, Yuzuru Iwasaki, Osamu Niwa, Tatsuya Tobita, Koji Suzuki

Research output: Contribution to journalArticlepeer-review

80 Citations (Scopus)

Abstract

A new type of the fiber-optic microsensor for surface plasmon resonance (SPR) was created on the basis of the fabrication technology of optical fiber probes in near-field scanning optical microscopy (NSOM). The newly developed SPR microsensors were prepared by coating a gold-metallic film on the chemically etched single-mode fiber containing a conical core. They were applied to the real-time monitoring of the refractive index (RI) of transparent liquids flowing in the microfluidic device. When SPR microsensors were chemically modified with a self-assembled monolayer presenting a hydroxyl group, they successfully responded to the refractive index from 1.33 to 1.40 RI with a sensitivity of 0.008 RI units that covers the interesting regions for SPR biosensor operated in a water solution.

Original languageEnglish
Pages (from-to)165-170
Number of pages6
JournalAnalytica Chimica Acta
Volume523
Issue number2
DOIs
Publication statusPublished - 2004 Oct 11

Keywords

  • Fiber-optic sensors
  • Microsensors
  • NSOM
  • SPR
  • Surface plasmon resonance

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy

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