Fiber-shaped artificial tissue with microvascular networks for bottom-up tissue reconstruction

Ryo Sato, Hiroaki Onoe

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

This paper describes a fiber-shaped microscale tissue with blood vessel networks. We co-cultured Hep-G2 (Human hepatic epithelial cell line) and HUVEC (human umbilical endothelial cell) in a collagen/alginate core-shell hydrogel microfiber fabricated by using a microfluidic device. We observed difference in construction of blood vessel networks in the hepatic tissue by varying in the ratio of co-cultured cells and the diameter of the core. In addition, by arranging the fiber-shaped tissues to construct macroscale tissue assembly, we confirmed the connection of blood vessel networks between the assembled fiber-shaped tissues.

Original languageEnglish
Title of host publication2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages247-250
Number of pages4
ISBN (Electronic)9781509050789
DOIs
Publication statusPublished - 2017 Feb 23
Event30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017 - Las Vegas, United States
Duration: 2017 Jan 222017 Jan 26

Other

Other30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017
CountryUnited States
CityLas Vegas
Period17/1/2217/1/26

Fingerprint

Tissue
blood vessels
Blood vessels
fibers
Fibers
cultured cells
microfibers
microfluidic devices
Hydrogel
Alginate
Endothelial cells
collagens
Microfluidics
Collagen
Hydrogels
microbalances
assembly
Cells

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Sato, R., & Onoe, H. (2017). Fiber-shaped artificial tissue with microvascular networks for bottom-up tissue reconstruction. In 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017 (pp. 247-250). [7863387] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MEMSYS.2017.7863387

Fiber-shaped artificial tissue with microvascular networks for bottom-up tissue reconstruction. / Sato, Ryo; Onoe, Hiroaki.

2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017. Institute of Electrical and Electronics Engineers Inc., 2017. p. 247-250 7863387.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Sato, R & Onoe, H 2017, Fiber-shaped artificial tissue with microvascular networks for bottom-up tissue reconstruction. in 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017., 7863387, Institute of Electrical and Electronics Engineers Inc., pp. 247-250, 30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017, Las Vegas, United States, 17/1/22. https://doi.org/10.1109/MEMSYS.2017.7863387
Sato R, Onoe H. Fiber-shaped artificial tissue with microvascular networks for bottom-up tissue reconstruction. In 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017. Institute of Electrical and Electronics Engineers Inc. 2017. p. 247-250. 7863387 https://doi.org/10.1109/MEMSYS.2017.7863387
Sato, Ryo ; Onoe, Hiroaki. / Fiber-shaped artificial tissue with microvascular networks for bottom-up tissue reconstruction. 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017. Institute of Electrical and Electronics Engineers Inc., 2017. pp. 247-250
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