Abstract
This paper describes a fiber-shaped microscale tissue with blood vessel networks. We co-cultured Hep-G2 (Human hepatic epithelial cell line) and HUVEC (human umbilical endothelial cell) in a collagen/alginate core-shell hydrogel microfiber fabricated by using a microfluidic device. We observed difference in construction of blood vessel networks in the hepatic tissue by varying in the ratio of co-cultured cells and the diameter of the core. In addition, by arranging the fiber-shaped tissues to construct macroscale tissue assembly, we confirmed the connection of blood vessel networks between the assembled fiber-shaped tissues.
| Original language | English |
|---|---|
| Title of host publication | 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017 |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Pages | 247-250 |
| Number of pages | 4 |
| ISBN (Electronic) | 9781509050789 |
| DOIs | |
| Publication status | Published - 2017 Feb 23 |
| Event | 30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017 - Las Vegas, United States Duration: 2017 Jan 22 → 2017 Jan 26 |
Other
| Other | 30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017 |
|---|---|
| Country | United States |
| City | Las Vegas |
| Period | 17/1/22 → 17/1/26 |
Fingerprint
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Mechanical Engineering
- Electrical and Electronic Engineering
Cite this
Fiber-shaped artificial tissue with microvascular networks for bottom-up tissue reconstruction. / Sato, Ryo; Onoe, Hiroaki.
2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017. Institute of Electrical and Electronics Engineers Inc., 2017. p. 247-250 7863387.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Fiber-shaped artificial tissue with microvascular networks for bottom-up tissue reconstruction
AU - Sato, Ryo
AU - Onoe, Hiroaki
PY - 2017/2/23
Y1 - 2017/2/23
N2 - This paper describes a fiber-shaped microscale tissue with blood vessel networks. We co-cultured Hep-G2 (Human hepatic epithelial cell line) and HUVEC (human umbilical endothelial cell) in a collagen/alginate core-shell hydrogel microfiber fabricated by using a microfluidic device. We observed difference in construction of blood vessel networks in the hepatic tissue by varying in the ratio of co-cultured cells and the diameter of the core. In addition, by arranging the fiber-shaped tissues to construct macroscale tissue assembly, we confirmed the connection of blood vessel networks between the assembled fiber-shaped tissues.
AB - This paper describes a fiber-shaped microscale tissue with blood vessel networks. We co-cultured Hep-G2 (Human hepatic epithelial cell line) and HUVEC (human umbilical endothelial cell) in a collagen/alginate core-shell hydrogel microfiber fabricated by using a microfluidic device. We observed difference in construction of blood vessel networks in the hepatic tissue by varying in the ratio of co-cultured cells and the diameter of the core. In addition, by arranging the fiber-shaped tissues to construct macroscale tissue assembly, we confirmed the connection of blood vessel networks between the assembled fiber-shaped tissues.
UR - http://www.scopus.com/inward/record.url?scp=85015725659&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85015725659&partnerID=8YFLogxK
U2 - 10.1109/MEMSYS.2017.7863387
DO - 10.1109/MEMSYS.2017.7863387
M3 - Conference contribution
AN - SCOPUS:85015725659
SP - 247
EP - 250
BT - 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017
PB - Institute of Electrical and Electronics Engineers Inc.
ER -