Abstract
This paper describes a fiber-shaped microscale tissue with blood vessel networks. We co-cultured Hep-G2 (Human hepatic epithelial cell line) and HUVEC (human umbilical endothelial cell) in a collagen/alginate core-shell hydrogel microfiber fabricated by using a microfluidic device. We observed difference in construction of blood vessel networks in the hepatic tissue by varying in the ratio of co-cultured cells and the diameter of the core. In addition, by arranging the fiber-shaped tissues to construct macroscale tissue assembly, we confirmed the connection of blood vessel networks between the assembled fiber-shaped tissues.
| Original language | English |
|---|---|
| Title of host publication | 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017 |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Pages | 247-250 |
| Number of pages | 4 |
| ISBN (Electronic) | 9781509050789 |
| DOIs | |
| Publication status | Published - 2017 Feb 23 |
| Event | 30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017 - Las Vegas, United States Duration: 2017 Jan 22 → 2017 Jan 26 |
Other
| Other | 30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017 |
|---|---|
| Country | United States |
| City | Las Vegas |
| Period | 17/1/22 → 17/1/26 |
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ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Mechanical Engineering
- Electrical and Electronic Engineering
Cite this
Sato, R., & Onoe, H. (2017). Fiber-shaped artificial tissue with microvascular networks for bottom-up tissue reconstruction. In 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017 (pp. 247-250). [7863387] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MEMSYS.2017.7863387