Finding of thiosulfate pathway for synthesis of organic sulfur compounds in Saccharomyces cerevisiae and improvement of ethanol production

Eri Funahashi, Kyohei Saiki, Kurara Honda, Yuki Sugiura, Yusuke Kawano, Iwao Ohtsu, Daisuke Watanabe, Yukari Wakabayashi, Tetsuya Abe, Tsuyoshi Nakanishi, Makoto Suematsu, Hiroshi Takagi

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

We found that Saccharomyces cerevisiae utilizes thiosulfate as a sole sulfur source. The energetically-favored thiosulfate rather than sulfate as sulfur sources is also more effective for improving growth and ethanol-production rate in S. cerevisiae due to high levels of intracellular NADPH during thiosulfate utilization.

Original languageEnglish
Pages (from-to)666-669
Number of pages4
JournalJournal of Bioscience and Bioengineering
Volume120
Issue number6
DOIs
Publication statusPublished - 2015 Dec 1

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Keywords

  • Ethanol production
  • Pentose phoshate pathway
  • Saccharomyces cerevisiae
  • Sulfur metabolism
  • Sulfur metabolome
  • Thiosulfate assimilation

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Bioengineering

Cite this

Funahashi, E., Saiki, K., Honda, K., Sugiura, Y., Kawano, Y., Ohtsu, I., Watanabe, D., Wakabayashi, Y., Abe, T., Nakanishi, T., Suematsu, M., & Takagi, H. (2015). Finding of thiosulfate pathway for synthesis of organic sulfur compounds in Saccharomyces cerevisiae and improvement of ethanol production. Journal of Bioscience and Bioengineering, 120(6), 666-669. https://doi.org/10.1016/j.jbiosc.2015.04.011