TY - JOUR
T1 - Flavonoid Constituents of Dracocephalum kotschyi Growing in Iran and Their Trypanocidal Activity
AU - Gohari, Ahmad Reza
AU - Saeidnia, Soodabeh
AU - Matsuo, Kenji
AU - Uchiyama, Nahoko
AU - Yagura, Toru
AU - Ito, Michiho
AU - Kiuchi, Fumiyuki
AU - Honda, Gisho
PY - 2003/12/1
Y1 - 2003/12/1
N2 - Nine flavonoids, calycopterin, xanthomicrol, isokaempferide, luteolin, apigenin, luteolin 7-O-β-D-glucopyranoside, luteolin 3′-O-β -D-glucuronide, apigenin 4′-O-β-D-glucopyranoside, and acacetin 7-O-β-D-glucopyranoside, together with a phenolic, rosmarinic acid, were isolated from the EtOAc and MeOH extracts of Dracocephalum kotschyi Boiss. Isokaempferide and apigenin showed lethality against epimastigotes of Trypanosoma cruzi, the etiological agent of Chagas disease.
AB - Nine flavonoids, calycopterin, xanthomicrol, isokaempferide, luteolin, apigenin, luteolin 7-O-β-D-glucopyranoside, luteolin 3′-O-β -D-glucuronide, apigenin 4′-O-β-D-glucopyranoside, and acacetin 7-O-β-D-glucopyranoside, together with a phenolic, rosmarinic acid, were isolated from the EtOAc and MeOH extracts of Dracocephalum kotschyi Boiss. Isokaempferide and apigenin showed lethality against epimastigotes of Trypanosoma cruzi, the etiological agent of Chagas disease.
KW - Dracocephalum kotschyi
KW - Flavonoid
KW - Labiatae
KW - Trypanocidal activity
KW - Trypanosoma cruzi
UR - http://www.scopus.com/inward/record.url?scp=0442278037&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0442278037&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0442278037
SN - 1861-0293
VL - 57
SP - 250
EP - 252
JO - Journal of Natural Medicines
JF - Journal of Natural Medicines
IS - 6
ER -
