Flow rate and fluence rate dependences of the triplet-state lifetime of talaporfin sodium photochemical reaction in flowing solution

Sayaka Ohmori, Shiho Hakomori, Tsunenori Arai

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The flow rate and fluence rate dependences of the triplet-state lifetime (τT) and singlet oxygen (1O2) luminescence intensity of a Talaporfin sodium (mono-L-aspartyl chlorin e6, Laserphyrin®) photochemical reaction in a flowing solution were studied. The oxygen consumption rate constant (k) did not proportionally increase as the fluence rate increased. The relationship between the static oxygen concentration in the flowing solution and τT was estimated. τT at the fluence rate of 0.8 × 104W/m2 was 16% longer than that at 0.2 × 104 W/m2 at the same oxygen concentration. The τT increase at the high-fluence rate is attributed to local and temporal oxygen depletion. The local and temporal oxygen depletion might cause the fluence-rate dependence nonproportionality of the measured k.

Original languageEnglish
Pages (from-to)1217-1219
Number of pages3
JournalJapanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers
Issue number3 A
Publication statusPublished - 2007 Mar 8



  • Flowing solution
  • Photodynamic therapy
  • Pulsed excitation
  • Singlet oxygen luminescence
  • Talaporfin sodium
  • Triplet state lifetime

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

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