Formal Total Synthesis of l -Ossamine via Decarboxylative Functionalization Using Visible-Light-Mediated Photoredox Catalysis in a Flow System

Shinsuke Inuki; Keisuke Sato; Takahide Fukuyama; Ilhyong Ryu; Yukari Fujimoto

doi:10.1021/acs.joc.6b02531

Formal Total Synthesis of l -Ossamine via Decarboxylative Functionalization Using Visible-Light-Mediated Photoredox Catalysis in a Flow System

Shinsuke Inuki, Keisuke Sato, Takahide Fukuyama, Ilhyong Ryu, Yukari Fujimoto

Department of Chemistry

Research output: Contribution to journal › Article

21 Citations (Scopus)

Abstract

A formal total synthesis of l-ossamine was achieved. The key feature of the synthesis was the decarboxylative functionalization of a threonine derivative using visible-light-mediated photoredox catalysis. This reaction was implemented in a flow reactor, allowing for the efficient conversion to the desired product.

Original language	English
Pages (from-to)	1248-1253
Number of pages	6
Journal	Journal of Organic Chemistry
Volume	82
Issue number	2
DOIs	https://doi.org/10.1021/acs.joc.6b02531
Publication status	Published - 2017 Jan 20

ASJC Scopus subject areas

Organic Chemistry

Access to Document

10.1021/acs.joc.6b02531

Fingerprint Dive into the research topics of 'Formal Total Synthesis of l -Ossamine via Decarboxylative Functionalization Using Visible-Light-Mediated Photoredox Catalysis in a Flow System'. Together they form a unique fingerprint.

Cite this

Inuki, S., Sato, K., Fukuyama, T., Ryu, I., & Fujimoto, Y. (2017). Formal Total Synthesis of l -Ossamine via Decarboxylative Functionalization Using Visible-Light-Mediated Photoredox Catalysis in a Flow System. Journal of Organic Chemistry, 82(2), 1248-1253. https://doi.org/10.1021/acs.joc.6b02531

@article{ecece43a4e774aff9f956ff81e99e0aa,

title = "Formal Total Synthesis of l -Ossamine via Decarboxylative Functionalization Using Visible-Light-Mediated Photoredox Catalysis in a Flow System",

abstract = "A formal total synthesis of l-ossamine was achieved. The key feature of the synthesis was the decarboxylative functionalization of a threonine derivative using visible-light-mediated photoredox catalysis. This reaction was implemented in a flow reactor, allowing for the efficient conversion to the desired product.",

author = "Shinsuke Inuki and Keisuke Sato and Takahide Fukuyama and Ilhyong Ryu and Yukari Fujimoto",

year = "2017",

month = jan,

day = "20",

doi = "10.1021/acs.joc.6b02531",

language = "English",

volume = "82",

pages = "1248--1253",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

number = "2",

}

TY - JOUR

T1 - Formal Total Synthesis of l -Ossamine via Decarboxylative Functionalization Using Visible-Light-Mediated Photoredox Catalysis in a Flow System

AU - Inuki, Shinsuke

AU - Sato, Keisuke

AU - Fukuyama, Takahide

AU - Ryu, Ilhyong

AU - Fujimoto, Yukari

PY - 2017/1/20

Y1 - 2017/1/20

N2 - A formal total synthesis of l-ossamine was achieved. The key feature of the synthesis was the decarboxylative functionalization of a threonine derivative using visible-light-mediated photoredox catalysis. This reaction was implemented in a flow reactor, allowing for the efficient conversion to the desired product.

AB - A formal total synthesis of l-ossamine was achieved. The key feature of the synthesis was the decarboxylative functionalization of a threonine derivative using visible-light-mediated photoredox catalysis. This reaction was implemented in a flow reactor, allowing for the efficient conversion to the desired product.

UR - http://www.scopus.com/inward/record.url?scp=85019383152&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85019383152&partnerID=8YFLogxK

U2 - 10.1021/acs.joc.6b02531

DO - 10.1021/acs.joc.6b02531

M3 - Article

C2 - 27997795

AN - SCOPUS:85019383152

VL - 82

SP - 1248

EP - 1253

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

SN - 0022-3263

IS - 2

ER -