Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer

Kenkichi Sasaki, Ayako Oyane, Koji Hyodo, Atsuo Ito, Yu Sogo, Masanobu Kamitakahara, Koji Ioku

Research output: Contribution to journalArticle

Abstract

A composite layer of fibroblast growth factor-2 (FGF-2) and low-crystalline apatite was formed on an ethylene-vinyl alcohol copolymer specimen using two types of aqueous calcium phosphate solutions supplemented with 10 μg·mL-1 FGF-2; one is a CP solution that is prepared by dissolving chemical reagents into ultrapure water and the other is an RKB solution that can be prepared by mixing clinically approved infusion fluids. In both solutions, a sufficient amount of FGF-2 for new skin tissue formation (1 μg·cm-2) was immobilized on the specimen surface.

Original languageEnglish
Pages (from-to)455-458
Number of pages4
JournalKey Engineering Materials
Volume361-363 I
Publication statusPublished - 2008
Externally publishedYes

Fingerprint

Apatites
Apatite
Fibroblast Growth Factor 2
Fibroblasts
Ethylene
Alcohols
Copolymers
Composite materials
Calcium phosphate
Skin
Tissue
Crystalline materials
Fluids
Intercellular Signaling Peptides and Proteins
ethylene-vinyl alcohol copolymer
Water

Keywords

  • Apatite
  • Bacterial infection
  • Composite
  • Ethylene-vinyl alcohol copolymer
  • FGF-2

ASJC Scopus subject areas

  • Ceramics and Composites
  • Chemical Engineering (miscellaneous)

Cite this

Sasaki, K., Oyane, A., Hyodo, K., Ito, A., Sogo, Y., Kamitakahara, M., & Ioku, K. (2008). Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer. Key Engineering Materials, 361-363 I, 455-458.

Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer. / Sasaki, Kenkichi; Oyane, Ayako; Hyodo, Koji; Ito, Atsuo; Sogo, Yu; Kamitakahara, Masanobu; Ioku, Koji.

In: Key Engineering Materials, Vol. 361-363 I, 2008, p. 455-458.

Research output: Contribution to journalArticle

Sasaki, K, Oyane, A, Hyodo, K, Ito, A, Sogo, Y, Kamitakahara, M & Ioku, K 2008, 'Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer', Key Engineering Materials, vol. 361-363 I, pp. 455-458.
Sasaki K, Oyane A, Hyodo K, Ito A, Sogo Y, Kamitakahara M et al. Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer. Key Engineering Materials. 2008;361-363 I:455-458.
Sasaki, Kenkichi ; Oyane, Ayako ; Hyodo, Koji ; Ito, Atsuo ; Sogo, Yu ; Kamitakahara, Masanobu ; Ioku, Koji. / Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer. In: Key Engineering Materials. 2008 ; Vol. 361-363 I. pp. 455-458.
@article{f59e1255e274416ea5d741497266a6de,
title = "Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer",
abstract = "A composite layer of fibroblast growth factor-2 (FGF-2) and low-crystalline apatite was formed on an ethylene-vinyl alcohol copolymer specimen using two types of aqueous calcium phosphate solutions supplemented with 10 μg·mL-1 FGF-2; one is a CP solution that is prepared by dissolving chemical reagents into ultrapure water and the other is an RKB solution that can be prepared by mixing clinically approved infusion fluids. In both solutions, a sufficient amount of FGF-2 for new skin tissue formation (1 μg·cm-2) was immobilized on the specimen surface.",
keywords = "Apatite, Bacterial infection, Composite, Ethylene-vinyl alcohol copolymer, FGF-2",
author = "Kenkichi Sasaki and Ayako Oyane and Koji Hyodo and Atsuo Ito and Yu Sogo and Masanobu Kamitakahara and Koji Ioku",
year = "2008",
language = "English",
volume = "361-363 I",
pages = "455--458",
journal = "Key Engineering Materials",
issn = "1013-9826",
publisher = "Trans Tech Publications",

}

TY - JOUR

T1 - Formation of FGF-2-apatite composite layer on ethylene-vinyl alcohol copolymer

AU - Sasaki, Kenkichi

AU - Oyane, Ayako

AU - Hyodo, Koji

AU - Ito, Atsuo

AU - Sogo, Yu

AU - Kamitakahara, Masanobu

AU - Ioku, Koji

PY - 2008

Y1 - 2008

N2 - A composite layer of fibroblast growth factor-2 (FGF-2) and low-crystalline apatite was formed on an ethylene-vinyl alcohol copolymer specimen using two types of aqueous calcium phosphate solutions supplemented with 10 μg·mL-1 FGF-2; one is a CP solution that is prepared by dissolving chemical reagents into ultrapure water and the other is an RKB solution that can be prepared by mixing clinically approved infusion fluids. In both solutions, a sufficient amount of FGF-2 for new skin tissue formation (1 μg·cm-2) was immobilized on the specimen surface.

AB - A composite layer of fibroblast growth factor-2 (FGF-2) and low-crystalline apatite was formed on an ethylene-vinyl alcohol copolymer specimen using two types of aqueous calcium phosphate solutions supplemented with 10 μg·mL-1 FGF-2; one is a CP solution that is prepared by dissolving chemical reagents into ultrapure water and the other is an RKB solution that can be prepared by mixing clinically approved infusion fluids. In both solutions, a sufficient amount of FGF-2 for new skin tissue formation (1 μg·cm-2) was immobilized on the specimen surface.

KW - Apatite

KW - Bacterial infection

KW - Composite

KW - Ethylene-vinyl alcohol copolymer

KW - FGF-2

UR - http://www.scopus.com/inward/record.url?scp=38149045875&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38149045875&partnerID=8YFLogxK

M3 - Article

VL - 361-363 I

SP - 455

EP - 458

JO - Key Engineering Materials

JF - Key Engineering Materials

SN - 1013-9826

ER -