Formation of parallel aq/org two-phase flows in extended-nanochannel by partial hydrophobic modification

Y. Kazoe, T. Ugajin, R. Ohta, K. Mawatari, T. Kitamori

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We report establishment of a nm-partial hydrophobic modification method by focused ion beam (FIB) and formation of parallel aqueous/organic two-phase flows in extended-nanochannels by control of liquid-liquid interface. Using the parallel two-phase flow, we demonstrated solvent extraction by integrating phase confluence, extraction and phase separation into 25 fL volume. Due to 103 times/sec interaction between solute molecules and surface by diffusion in 100 nm space, extraction of lipid into the organic phase was completed within 4.5 ms. The ultra high performance compared to microfluidics will greatly contribute to novel applications such as single cell analysis.

Original languageEnglish
Title of host publicationMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages1029-1031
Number of pages3
ISBN (Electronic)9780979806483
Publication statusPublished - 2015 Jan 1
Externally publishedYes
Event19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of
Duration: 2015 Oct 252015 Oct 29

Publication series

NameMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Other

Other19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
CountryKorea, Republic of
CityGyeongju
Period15/10/2515/10/29

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Keywords

  • Extraction
  • Nanofluidics
  • Two-phase flow

ASJC Scopus subject areas

  • Control and Systems Engineering

Cite this

Kazoe, Y., Ugajin, T., Ohta, R., Mawatari, K., & Kitamori, T. (2015). Formation of parallel aq/org two-phase flows in extended-nanochannel by partial hydrophobic modification. In MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1029-1031). (MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.