TY - JOUR
T1 - Four hepatosplenic T-cell lymphoma cases of Japanese patients
AU - Kawai, Hidetsugu
AU - Matsushita, Hiromichi
AU - Ohmachi, Ken
AU - Kojima, Minoru
AU - Machida, Shinichiro
AU - Ogawa, Yoshiaki
AU - Kawada, Hiroshi
AU - Nakamura, Naoya
AU - Ando, Kiyoshi
N1 - Publisher Copyright:
© 2015 The Authors.
PY - 2016
Y1 - 2016
N2 - Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an elderly case that was 74 years of age, were not at adolescence. No cases had a history of immunodeficiency. All other disease phenotypes were similar to the typical HSTCL cases. These findings suggest that there are a certain proportion of HSTCL patients who presented after middle age.
AB - Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an elderly case that was 74 years of age, were not at adolescence. No cases had a history of immunodeficiency. All other disease phenotypes were similar to the typical HSTCL cases. These findings suggest that there are a certain proportion of HSTCL patients who presented after middle age.
KW - Elderly patients
KW - Hepatosplenic T-cell lymphoma
KW - Immunodeficiency
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U2 - 10.1016/j.lrr.2015.12.001
DO - 10.1016/j.lrr.2015.12.001
M3 - Article
AN - SCOPUS:84950327221
SN - 2213-0489
VL - 5
SP - 3
EP - 6
JO - Leukemia Research Reports
JF - Leukemia Research Reports
ER -