Functional imaging system for simultaneous measurement of blood volume and flow

Yohei Watanabe, Hitoshi Fujii, Eiji Okada

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Optical imaging derived from intrinsic signals such as blood volume and flow has enabled us to characterize the area of brain activation. Multi-spectral imaging of the change in cortical reflectance allows the determination of the change in the oxy-hemoglobin concentration independent of the deoxy-haemoglobin concentration. The changes in blood volume and oxygenation are closely related to the cerebral blood flow, and hence the simultaneous measurement of blood volume and flow in the cortical tissue must be beneficial for investigation of functional brain activation. Laser speckle flowgraphy has also been developed to visualize the blood flow in tissue and has been applied to measure the blood flow in tissue. In this study, a functional imaging system has been designed and assembled for the simultaneous measurement of the change in blood volume and flow in tissue. The optical systems of multi-spectral imaging and laser speckle flowgraphy are attached to the photo ports of the beam-splitter attachment of a stereo-microscope. The data of the multi-spectral image and speckle pattern of phantoms and finger are obtained for the initial experiments with the proposed system.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsD.A. Boas
Pages231-238
Number of pages8
Volume5138
Publication statusPublished - 2003
EventPhoton Migration and Diffuse-Light Imaging - Munich, Germany
Duration: 2003 Jun 222003 Jun 23

Other

OtherPhoton Migration and Diffuse-Light Imaging
CountryGermany
CityMunich
Period03/6/2203/6/23

Fingerprint

blood volume
blood flow
Imaging systems
Blood
Speckle
Tissue
Hemoglobin
brain
Imaging techniques
Brain
activation
oxyhemoglobin
Chemical activation
oxygenation
speckle patterns
hemoglobin
beam splitters
Oxygenation
Lasers
lasers

Keywords

  • Blood flow
  • Blood volume
  • Functional imaging
  • Laser speckle flowgraphy
  • Multi-spectral imaging

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Watanabe, Y., Fujii, H., & Okada, E. (2003). Functional imaging system for simultaneous measurement of blood volume and flow. In D. A. Boas (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 5138, pp. 231-238)

Functional imaging system for simultaneous measurement of blood volume and flow. / Watanabe, Yohei; Fujii, Hitoshi; Okada, Eiji.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / D.A. Boas. Vol. 5138 2003. p. 231-238.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Watanabe, Y, Fujii, H & Okada, E 2003, Functional imaging system for simultaneous measurement of blood volume and flow. in DA Boas (ed.), Proceedings of SPIE - The International Society for Optical Engineering. vol. 5138, pp. 231-238, Photon Migration and Diffuse-Light Imaging, Munich, Germany, 03/6/22.
Watanabe Y, Fujii H, Okada E. Functional imaging system for simultaneous measurement of blood volume and flow. In Boas DA, editor, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 5138. 2003. p. 231-238
Watanabe, Yohei ; Fujii, Hitoshi ; Okada, Eiji. / Functional imaging system for simultaneous measurement of blood volume and flow. Proceedings of SPIE - The International Society for Optical Engineering. editor / D.A. Boas. Vol. 5138 2003. pp. 231-238
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