Functional lateralization of speech processing in adults and children who stutter

Yutaka Sato, Koichi Mori, Toshizo Koizumi, Yasuyo Minagawa, Akihiro Tanaka, Emi Ozawa, Yoko Wakaba, Reiko Mazuka

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Developmental stuttering is a speech disorder in fluency characterized by repetitions, prolongations, and silent blocks, especially in the initial parts of utterances. Although their symptoms are motor related, people who stutter show abnormal patterns of cerebral hemispheric dominance in both anterior and posterior language areas. It is unknown whether the abnormal functional lateralization in the posterior language area starts during childhood or emerges as a consequence of many years of stuttering. In order to address this issue, we measured the lateralization of hemodynamic responses in the auditory cortex during auditory speech processing in adults and children who stutter, including preschoolers, with nearinfrared spectroscopy. We used the analysis-resynthesis technique to prepare two types of stimuli: (i) a phonemic contrast embedded in Japanese spoken words (/itta/ vs. /itte/) and (ii) a prosodic contrast (/itta/ vs. /itta?/). In the baseline blocks, only /itta/ tokens were presented. In phonemic contrast blocks, /itta/ and /itte/ tokens were presented pseudo-randomly, and /itta/ and /itta?/ tokens in prosodic contrast blocks. In adults and children who do not stutter, there was a clear left-hemispheric advantage for the phonemic contrast compared to the prosodic contrast. Adults and children who stutter, however, showed no significant difference between the two stimulus conditions. A subject-by-subject analysis revealed that not a single subject who stutters showed a left advantage in the phonemic contrast over the prosodic contrast condition. These results indicate that the functional lateralization for auditory speech processing is in disarray among those who stutter, even at preschool age. These results shed light on the neural pathophysiology of developmental stuttering.

Original languageEnglish
Article numberArticle 70
JournalFrontiers in Psychology
Volume2
Issue numberAPR
DOIs
Publication statusPublished - 2011

Fingerprint

Stuttering
Language
Cerebral Dominance
Speech Disorders
Auditory Cortex
Spectrum Analysis
Hemodynamics

Keywords

  • Cerebral lateralization
  • Developmental stuttering
  • Language development

ASJC Scopus subject areas

  • Psychology(all)

Cite this

Functional lateralization of speech processing in adults and children who stutter. / Sato, Yutaka; Mori, Koichi; Koizumi, Toshizo; Minagawa, Yasuyo; Tanaka, Akihiro; Ozawa, Emi; Wakaba, Yoko; Mazuka, Reiko.

In: Frontiers in Psychology, Vol. 2, No. APR, Article 70, 2011.

Research output: Contribution to journalArticle

Sato, Y, Mori, K, Koizumi, T, Minagawa, Y, Tanaka, A, Ozawa, E, Wakaba, Y & Mazuka, R 2011, 'Functional lateralization of speech processing in adults and children who stutter', Frontiers in Psychology, vol. 2, no. APR, Article 70. https://doi.org/10.3389/fpsyg.2011.00070
Sato, Yutaka ; Mori, Koichi ; Koizumi, Toshizo ; Minagawa, Yasuyo ; Tanaka, Akihiro ; Ozawa, Emi ; Wakaba, Yoko ; Mazuka, Reiko. / Functional lateralization of speech processing in adults and children who stutter. In: Frontiers in Psychology. 2011 ; Vol. 2, No. APR.
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