Functional visual acuity assessment of severe atopic keratoconjunctivitis

Osama M A Ibrahim, Murat Dogru, Minako Kaido, Takashi Kojima, Hiroshi Fujishima, Kazuo Tsubota

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

PURPOSE: To evaluate changes in functional visual acuity (FVA) measurements before and after treatment with 0.1% cyclosporine ophthalmic solution for 3 months in patients with severe atopic keratoconjunctivitis (AKC).

METHODS: Pairs of eyes were analyzed from 3 boys (mean age 9 ± 3.6 years) who complained of having severe AKC and were recruited for the study. Conventional Landolt visual acuity, FVA, and visual maintenance ratio (VMR) measurements were conducted before and after 3 months of 0.1% cyclosporine eye drop treatment. Tear film lipid layer interferometry, tear film break-up time, fluorescein and rose bengal vital stainings, and the Schirmer test were also performed before and after treatment.

RESULTS: Eye drop treatment was associated not only with improvement of tear function and ocular surface status but also with better quality of visual function. The mean logarithm of the minimum angle of resolution FVA and Landolt visual acuity values improved from 0.45 ± 0.26 and 0.13 ± 0.17 before treatment to 0.16 ± 0.03 and -0.06 ± 0.05 after treatment, respectively. Similarly, the mean VMR values were markedly improved from 0.88 ± 0.06 to 0.95 ± 0.03 after treatment.

CONCLUSIONS: FVA and VMR are promising parameters in the assessment of dynamic visual acuity changes in AKC-affected patients and evaluation of treatment outcome.

Original languageEnglish
Pages (from-to)S13-S18
JournalCornea
Volume33
DOIs
Publication statusPublished - 2014 Nov 1

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Keratoconjunctivitis
Visual Acuity
Ophthalmic Solutions
Tears
Maintenance
Therapeutics
Cyclosporine
Interferometry
Rose Bengal
Fluorescein
Staining and Labeling
Lipids

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ibrahim, O. M. A., Dogru, M., Kaido, M., Kojima, T., Fujishima, H., & Tsubota, K. (2014). Functional visual acuity assessment of severe atopic keratoconjunctivitis. Cornea, 33, S13-S18. https://doi.org/10.1097/ICO.0000000000000245

Functional visual acuity assessment of severe atopic keratoconjunctivitis. / Ibrahim, Osama M A; Dogru, Murat; Kaido, Minako; Kojima, Takashi; Fujishima, Hiroshi; Tsubota, Kazuo.

In: Cornea, Vol. 33, 01.11.2014, p. S13-S18.

Research output: Contribution to journalArticle

Ibrahim, OMA, Dogru, M, Kaido, M, Kojima, T, Fujishima, H & Tsubota, K 2014, 'Functional visual acuity assessment of severe atopic keratoconjunctivitis', Cornea, vol. 33, pp. S13-S18. https://doi.org/10.1097/ICO.0000000000000245
Ibrahim, Osama M A ; Dogru, Murat ; Kaido, Minako ; Kojima, Takashi ; Fujishima, Hiroshi ; Tsubota, Kazuo. / Functional visual acuity assessment of severe atopic keratoconjunctivitis. In: Cornea. 2014 ; Vol. 33. pp. S13-S18.
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