Functionalization of hollow nanoparticles fabricated by the layer-by-layer deposition

Tomonori Toyoda, Keiji Fujimoto

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We prepared hollow particles in nano size using a layer-by-layer deposition. Liposomes were used as a template for the layer-by-layer deposition. At first, negatively charged liposomes were prepared from dilauroyl phosphatidic acid (DLPA) and dimyristoyl phosphatidylcholine (DMPC). Poly-L-lysine (PLys) and poly-L-aspartic acid (PAsp) were used as adsorbates. When the alternative adsorption of PLys and PAsp on the liposomes was repeated for thickening the capsule layer, their ζ-potentials changed between positive and negative charges at each deposition. To investigate the release from liposomes and liposome-polypeptide complex, 1-hydroxypyrene-3,6,8-trisulfonic acid (HPTS) was incorporated. From the leakage experiment in a buffered solution, we found that the adsorption of polymers was related to the release from hollow particles, and the leakage was completely inhibited by the deposition above 400ppm of PLys.

Original languageEnglish
Title of host publicationPolymer Preprints, Japan
Pages1553
Number of pages1
Volume54
Edition1
Publication statusPublished - 2005
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: 2005 May 252005 May 27

Other

Other54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period05/5/2505/5/27

Fingerprint

Liposomes
Nanoparticles
Acids
Adsorption
Polypeptides
Leakage (fluid)
Adsorbates
Polymers
Experiments

Keywords

  • Hollow particle
  • Layer-by-Layer
  • Nanoparticle

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Toyoda, T., & Fujimoto, K. (2005). Functionalization of hollow nanoparticles fabricated by the layer-by-layer deposition. In Polymer Preprints, Japan (1 ed., Vol. 54, pp. 1553)

Functionalization of hollow nanoparticles fabricated by the layer-by-layer deposition. / Toyoda, Tomonori; Fujimoto, Keiji.

Polymer Preprints, Japan. Vol. 54 1. ed. 2005. p. 1553.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Toyoda, T & Fujimoto, K 2005, Functionalization of hollow nanoparticles fabricated by the layer-by-layer deposition. in Polymer Preprints, Japan. 1 edn, vol. 54, pp. 1553, 54th SPSJ Annual Meeting 2005, Yokohama, Japan, 05/5/25.
Toyoda T, Fujimoto K. Functionalization of hollow nanoparticles fabricated by the layer-by-layer deposition. In Polymer Preprints, Japan. 1 ed. Vol. 54. 2005. p. 1553
Toyoda, Tomonori ; Fujimoto, Keiji. / Functionalization of hollow nanoparticles fabricated by the layer-by-layer deposition. Polymer Preprints, Japan. Vol. 54 1. ed. 2005. pp. 1553
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