G-language System as a platform for large-scale analysis of high-throughput omics data

Research output: Contribution to journalReview article

26 Citations (Scopus)

Abstract

The advent of high-throughput measurement technologies has resulted in the rapid accumulation of "omics" information including genome, transcriptome, proteome, and metabolome data. This increase in data acquisition has lead to a demand for an efficient computational platform for in silico analysis. The G-language software suite provides a comprehensive workbench for large-scale omics research and systems biology. The suite includes a bioinformatics research framework G-language Genome Analysis Environment, which contains a Gene Prediction Accuracy Classification benchmarking tool for the quantification of the sensitivity of genome informatics analysis methods to genome annotation completeness. Omics data processed in this environment can be visualized with KEGG-based pathway mapping web service, and Genome-based Modeling System enables automatic prototyping of metabolic pathway models from the genome. The software suite covers various domains of omics, with the goal of integrating all of these data for research into systems biology.

Original languageEnglish
Pages (from-to)282-288
Number of pages7
JournalJournal of Pesticide Science
Volume31
Issue number3
DOIs
Publication statusPublished - 2006 Aug 31

Keywords

  • Analysis pipelines
  • Bioinformatics
  • G-language System
  • Omics
  • Post-genome
  • Software tools
  • Systems biology

ASJC Scopus subject areas

  • Insect Science
  • Health, Toxicology and Mutagenesis

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