Ganglioside-binding Peptides selected from a Combinatorial Library and Their Carbohydrate Recognition

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2 Citations (Scopus)

Abstract

Proteins such as lectins, enzymes, and antibodies, have been employed in the investigation of protein-carbohydrate interaction. However, it is very difficult to design molecules that bind specifically to a target carbohydrate. In my study, selection of ganglioside-binding peptides from a combinatorial random peptide library was carried out. The selected peptides specifically bound to the ganglioside and were suggested to have interacted with carbohydrate through a consensus motif.

Original languageEnglish
Pages (from-to)557
Number of pages1
JournalTrends in Glycoscience and Glycotechnology
Volume13
Issue number73
Publication statusPublished - 2001 Sep
Externally publishedYes

Fingerprint

Gangliosides
Carbohydrates
Peptides
Peptide Library
Lectins
Proteins
Molecules
Antibodies
Enzymes

Keywords

  • Carbohydrate recognition
  • Ganglioside
  • Peptide library
  • Phage display

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry

Cite this

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