Gastroparesis: Current concepts and management

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28 Citations (Scopus)


Delayed gastric emptying in the absence of mechanical obstruction is referred to as gastroparesis. Symptoms that are often attributed to gastroparesis include postprandial fullness, nausea, and vomiting. Although tests of gastric motor function may aid diagnostic labeling, their contribution to determining the treatment approach is often limited. Although clinical suspicion of gastroparesis warrants the exclusion of mechanical causes and serum electrolyte imbalances, followed by empirical treatment with a gastroprokinetic such as domperidone or metoclopramide, evidence that these drugs are effective for patients with gastroparesis is far from overwhelming. In refractory cases with severe weight loss, invasive therapeutics such as inserting a feeding jejunostomy tube, intrapyloric injection of botulinum toxin, surgical (partial) gastrectomy, and implantable gastric electrical stimulation are occasionally considered.

Original languageEnglish
Pages (from-to)166-173
Number of pages8
JournalGut and Liver
Issue number3
Publication statusPublished - 2009 Sep 1
Externally publishedYes


  • Delayed gastric emptying
  • Diabetes mellitus
  • Gastric electrical stimulation
  • Gastroparesis
  • Prokinetic therapy

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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