Generation of 2-substituted-2-metallo-1,3-dithianes and their coupling with 1,2-disubstituted epoxides at room temperature

Mitsuaki Ide, Minora Yasuda, Masaya Nakata

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

2-Substituted-1,3-dithianes were subjected to lithiation by n-BuLi at room temperature and the resulting anions reacted with 1,2-disubstituted epoxides at room temperature, giving the coupling products in satisfactory yield. In addition, a mixed organometallic reagent, n-BuLi/Bu2Mg, was found to be an effective metallation reagent for 2-substituted-1,3-dithianes.

Original languageEnglish
Pages (from-to)936-938
Number of pages3
JournalSynlett
Issue number8
DOIs
Publication statusPublished - 1998 Aug

    Fingerprint

ASJC Scopus subject areas

  • Organic Chemistry

Cite this