Generation of monodisperse cell-sized microdroplets using a centrifuge-based axisymmetric co-flowing microfluidic device

Hitoyoshi Yamashita, Masamune Morita, Haruka Sugiura, Kei Fujiwara, Hiroaki Onoe, Masahiro Takinoue

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

We report an easy-to-use generation method of biologically compatible monodisperse water-in-oil microdroplets using a glass-capillary-based microfluidic device in a tabletop mini-centrifuge. This device does not require complicated microfabrication; furthermore, only a small sample volume is required in experiments. Therefore, we believe that this method will assist biochemical and cell-biological experiments.

Original languageEnglish
Pages (from-to)492-495
Number of pages4
JournalJournal of Bioscience and Bioengineering
Volume119
Issue number4
DOIs
Publication statusPublished - 2015 Apr 1

Keywords

  • Biochemical reactions
  • Cell encapsulation
  • Centrifuge
  • Microfluidic device
  • Monodisperse microdroplets
  • Plateau-Rayleigh instability

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

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