Giant fold gastritis induced by epoprostenol infusion in patients with pulmonary arterial hypertension

Yohei Miura; Masaharu Kataoka; Tomohiro Chiba; Takumi Inami; Hideaki Yoshino; Toru Satoh

doi:10.1253/circj.CJ-18-0349

Giant fold gastritis induced by epoprostenol infusion in patients with pulmonary arterial hypertension

Yohei Miura, Masaharu Kataoka, Tomohiro Chiba, Takumi Inami, Hideaki Yoshino, Toru Satoh

Department of Internal Medicine (Cardiology)

Research output: Contribution to journal › Article

Abstract

Background: Epoprostenol infusion is the strongest and most convincing therapeutic strategy for severe pulmonary arterial hypertension (PAH). This study investigated the gastrointestinal side effects of epoprostenol. Methods and Results: The study group of 12 patients treated with epoprostenol (epoprostenol group) and 4 patients without epoprostenol (control group) underwent stomach barium examination, which revealed that the prevalence of giant fold gastritis was significantly higher in the patients treated with epoprostenol (75% in epoprostenol group vs. 0% in control group; P=0.019). Conclusions: Giant fold gastritis may be an important side effect of epoprostenol infusion.

Original language	English
Pages (from-to)	2676-2677
Number of pages	2
Journal	Circulation Journal
Volume	82
Issue number	10
DOIs	https://doi.org/10.1253/circj.CJ-18-0349
Publication status	Published - 2018 Jan 1

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Keywords

Epoprostenol
Giant fold gastritis
Pulmonary arterial hypertension
Stomach barium examination

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Cite this

Miura, Y., Kataoka, M., Chiba, T., Inami, T., Yoshino, H., & Satoh, T. (2018). Giant fold gastritis induced by epoprostenol infusion in patients with pulmonary arterial hypertension. Circulation Journal, 82(10), 2676-2677. https://doi.org/10.1253/circj.CJ-18-0349

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abstract = "Background: Epoprostenol infusion is the strongest and most convincing therapeutic strategy for severe pulmonary arterial hypertension (PAH). This study investigated the gastrointestinal side effects of epoprostenol. Methods and Results: The study group of 12 patients treated with epoprostenol (epoprostenol group) and 4 patients without epoprostenol (control group) underwent stomach barium examination, which revealed that the prevalence of giant fold gastritis was significantly higher in the patients treated with epoprostenol (75% in epoprostenol group vs. 0% in control group; P=0.019). Conclusions: Giant fold gastritis may be an important side effect of epoprostenol infusion.",

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AU - Yoshino, Hideaki

AU - Satoh, Toru

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10.1253/circj.CJ-18-0349