Glycoprotein nanotube traps influenza virus

Shuta Yuge, Motofusa Akiyama, Makoto Ishii, Ho Namkoong, Kazuma Yagi, Yoko Nakai, Ryo Adachi, Teruyuki Komatsu

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We report the synthesis, structure, and influenza A virus trapping capability of protein nanotubes with an internal wall of fetuin glycoprotein. The nanotubes were fabricated via the alternating layer-by-layer assembly of human serum albumin (HSA), poly-L-arginine (PLA), and fetuin into a track-etched polycarbonate (PC) membrane (pore size, 800 nm), followed by dissolution of the PC template. In an aqueous medium, the (PLA/HSA)5 PLA/fetuin nanotubes captured influenza A virus PR8 (H1N1) efficiently, as revealed by ELISA measurements.

Original languageEnglish
Pages (from-to)95-97
Number of pages3
JournalChemistry Letters
Volume46
Issue number1
DOIs
Publication statusPublished - 2017

Fingerprint

polycarbonate
Fetuins
Viruses
Nanotubes
Glycoproteins
Serum Albumin
Pore size
Dissolution
Membranes
polyarginine
Proteins

Keywords

  • Fetuin glycoprotein
  • Influenza virus
  • Layer-by-layer assembly

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Yuge, S., Akiyama, M., Ishii, M., Namkoong, H., Yagi, K., Nakai, Y., ... Komatsu, T. (2017). Glycoprotein nanotube traps influenza virus. Chemistry Letters, 46(1), 95-97. https://doi.org/10.1246/cl.160805

Glycoprotein nanotube traps influenza virus. / Yuge, Shuta; Akiyama, Motofusa; Ishii, Makoto; Namkoong, Ho; Yagi, Kazuma; Nakai, Yoko; Adachi, Ryo; Komatsu, Teruyuki.

In: Chemistry Letters, Vol. 46, No. 1, 2017, p. 95-97.

Research output: Contribution to journalArticle

Yuge, S, Akiyama, M, Ishii, M, Namkoong, H, Yagi, K, Nakai, Y, Adachi, R & Komatsu, T 2017, 'Glycoprotein nanotube traps influenza virus', Chemistry Letters, vol. 46, no. 1, pp. 95-97. https://doi.org/10.1246/cl.160805
Yuge S, Akiyama M, Ishii M, Namkoong H, Yagi K, Nakai Y et al. Glycoprotein nanotube traps influenza virus. Chemistry Letters. 2017;46(1):95-97. https://doi.org/10.1246/cl.160805
Yuge, Shuta ; Akiyama, Motofusa ; Ishii, Makoto ; Namkoong, Ho ; Yagi, Kazuma ; Nakai, Yoko ; Adachi, Ryo ; Komatsu, Teruyuki. / Glycoprotein nanotube traps influenza virus. In: Chemistry Letters. 2017 ; Vol. 46, No. 1. pp. 95-97.
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