Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells

Sonja Johannsmeier, Patrick Heeger, Mitsuhiro Terakawa, Stefan Kalies, Alexander Heisterkamp, Tammo Ripken, Dag Heinemann

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Gold nanoparticle mediated laser stimulation of neuronal cells allows for cell activation on a single-cell level. It could therefore be considered an alternative to classical electric neurostimulation. The physiological impact of this new approach has not been intensively studied so far. Here, we investigate the targeted cell's reaction to a laser stimulus based on its calcium response. A complex cellular reaction involving multiple sources has been revealed.

Original languageEnglish
Title of host publicationMedical Laser Applications and Laser-Tissue Interactions VIII
PublisherSPIE
Volume10417
ISBN (Electronic)9781510612921
DOIs
Publication statusPublished - 2017
EventMedical Laser Applications and Laser-Tissue Interactions VIII 2017 - Munich, Germany
Duration: 2017 Jun 252017 Jun 29

Other

OtherMedical Laser Applications and Laser-Tissue Interactions VIII 2017
CountryGermany
CityMunich
Period17/6/2517/6/29

Fingerprint

stimulation
Gold
Nanoparticles
Lasers
gold
nanoparticles
causes
cells
lasers
Calcium
Chemical activation
stimuli
calcium
activation

Keywords

  • Gold nanoparticles
  • Laser-cell-interaction
  • Neuroimplants
  • Neurostimulation
  • Stress signaling

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Johannsmeier, S., Heeger, P., Terakawa, M., Kalies, S., Heisterkamp, A., Ripken, T., & Heinemann, D. (2017). Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells. In Medical Laser Applications and Laser-Tissue Interactions VIII (Vol. 10417). [104170B] SPIE. https://doi.org/10.1117/12.2284174

Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells. / Johannsmeier, Sonja; Heeger, Patrick; Terakawa, Mitsuhiro; Kalies, Stefan; Heisterkamp, Alexander; Ripken, Tammo; Heinemann, Dag.

Medical Laser Applications and Laser-Tissue Interactions VIII. Vol. 10417 SPIE, 2017. 104170B.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Johannsmeier, S, Heeger, P, Terakawa, M, Kalies, S, Heisterkamp, A, Ripken, T & Heinemann, D 2017, Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells. in Medical Laser Applications and Laser-Tissue Interactions VIII. vol. 10417, 104170B, SPIE, Medical Laser Applications and Laser-Tissue Interactions VIII 2017, Munich, Germany, 17/6/25. https://doi.org/10.1117/12.2284174
Johannsmeier S, Heeger P, Terakawa M, Kalies S, Heisterkamp A, Ripken T et al. Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells. In Medical Laser Applications and Laser-Tissue Interactions VIII. Vol. 10417. SPIE. 2017. 104170B https://doi.org/10.1117/12.2284174
Johannsmeier, Sonja ; Heeger, Patrick ; Terakawa, Mitsuhiro ; Kalies, Stefan ; Heisterkamp, Alexander ; Ripken, Tammo ; Heinemann, Dag. / Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells. Medical Laser Applications and Laser-Tissue Interactions VIII. Vol. 10417 SPIE, 2017.
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