Abstract
A 25-year-old chronically immunosuppressed woman with systemic lupus erythematosus (SLE) died after developing subacute granulomatous encephalitis caused by Acanthamoeba. Amoebic trophozoites were also found in the lung, suggesting a primary pulmonary focus of infection. The infectious encephalitis was difficult to differentiate from a flare-up of central nervous system lupus. This case illustrates that Acanthamoeba can cause fatal encephalitis in lupus patients, as well as in patients with acquired immunodeficiency syndrome as previously reported. To our knowledge, this is the first reported case of granulomatous amoebic encephalitis due to Acanthamoeba in a patient with SLE.
| Original language | English |
|---|---|
| Pages (from-to) | 329-332 |
| Number of pages | 4 |
| Journal | Clinical Rheumatology |
| Volume | 17 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1998 |
| Externally published | Yes |
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Keywords
- Acanthamoeba
- Granulomatous amoebic encephalitis
- Opportunistic Infection
- Systemic lupus erythematosus
ASJC Scopus subject areas
- Rheumatology
- Immunology
Cite this
Granulomatous amoebic encephalitis caused by Acanthamoeba in a patient with systemic lupus erythematosus. / Koide, J.; Okusawa, E.; Ito, T.; Mori, S.; Takeuchi, Tsutomu; Itoyama, S.; Abe, T.
In: Clinical Rheumatology, Vol. 17, No. 4, 1998, p. 329-332.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Granulomatous amoebic encephalitis caused by Acanthamoeba in a patient with systemic lupus erythematosus
AU - Koide, J.
AU - Okusawa, E.
AU - Ito, T.
AU - Mori, S.
AU - Takeuchi, Tsutomu
AU - Itoyama, S.
AU - Abe, T.
PY - 1998
Y1 - 1998
N2 - A 25-year-old chronically immunosuppressed woman with systemic lupus erythematosus (SLE) died after developing subacute granulomatous encephalitis caused by Acanthamoeba. Amoebic trophozoites were also found in the lung, suggesting a primary pulmonary focus of infection. The infectious encephalitis was difficult to differentiate from a flare-up of central nervous system lupus. This case illustrates that Acanthamoeba can cause fatal encephalitis in lupus patients, as well as in patients with acquired immunodeficiency syndrome as previously reported. To our knowledge, this is the first reported case of granulomatous amoebic encephalitis due to Acanthamoeba in a patient with SLE.
AB - A 25-year-old chronically immunosuppressed woman with systemic lupus erythematosus (SLE) died after developing subacute granulomatous encephalitis caused by Acanthamoeba. Amoebic trophozoites were also found in the lung, suggesting a primary pulmonary focus of infection. The infectious encephalitis was difficult to differentiate from a flare-up of central nervous system lupus. This case illustrates that Acanthamoeba can cause fatal encephalitis in lupus patients, as well as in patients with acquired immunodeficiency syndrome as previously reported. To our knowledge, this is the first reported case of granulomatous amoebic encephalitis due to Acanthamoeba in a patient with SLE.
KW - Acanthamoeba
KW - Granulomatous amoebic encephalitis
KW - Opportunistic Infection
KW - Systemic lupus erythematosus
UR - http://www.scopus.com/inward/record.url?scp=0031694537&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031694537&partnerID=8YFLogxK
U2 - 10.1007/BF01451015
DO - 10.1007/BF01451015
M3 - Article
C2 - 9776118
AN - SCOPUS:0031694537
VL - 17
SP - 329
EP - 332
JO - Clinical Rheumatology
JF - Clinical Rheumatology
SN - 0770-3198
IS - 4
ER -