TY - JOUR
T1 - Grubbs carbene complex-catalyzed cleavage of allyl vic-diols to aldehydes with a co-oxidant
T2 - Application to the selective cleavage of huge marine molecules
AU - Han, Chunguang
AU - Yamano, Yoshi
AU - Kakiuchi, Fumitoshi
AU - Nakamura, Kazuhiko
AU - Uemura, Daisuke
N1 - Funding Information:
This work was supported in part by a Grant-in-Aid for Creative Scientific Research ( 16GS0206 ) from JSPS , and by the G-COE program in chemistry at Nagoya University from the Ministry of Education, Science, Sports and Culture , Japan.
PY - 2011/12/9
Y1 - 2011/12/9
N2 - An oxidative cleavage of allyl vic-diols to aldehydes catalyzed by a Grubbs carbene complex using a co-oxidant has been established for the first time, with good yields. The utility of this selective cleavage reaction was demonstrated through the use of two huge marine molecules, symbiodinolide and N-p-BrBz palytoxin.
AB - An oxidative cleavage of allyl vic-diols to aldehydes catalyzed by a Grubbs carbene complex using a co-oxidant has been established for the first time, with good yields. The utility of this selective cleavage reaction was demonstrated through the use of two huge marine molecules, symbiodinolide and N-p-BrBz palytoxin.
KW - Catalytic reaction
KW - Degradation reaction
KW - Grubbs carbene complex
KW - Marine huge molecule
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U2 - 10.1016/j.tet.2011.09.002
DO - 10.1016/j.tet.2011.09.002
M3 - Article
AN - SCOPUS:80555150659
SN - 0040-4020
VL - 67
SP - 9622
EP - 9626
JO - Tetrahedron
JF - Tetrahedron
IS - 49
ER -
