Hürthle cell tumor of the thyroid: Analysis of 188 cases

K. Sugino, K. Ito, T. Mimura, Kaori Kameyama, H. Iwasaki, K. Ito

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

We reviewed 188 cases of Hürthle cell tumor of the thyroid (HCT) between 1982 and 1996. There were 160 women and 28 men with a mean age of 51.8 years. Thirty-one of the patients had cancer, and the others had adenoma. Age, size of the primary tumor, and preoperative thyroglobulin level were not significantly different in the cancer and adenoma patients. The gender ratio, however, was significantly different (p < 0.05). Recurrent HCT was observed in three patients with adenoma. Two patients had subcutaneous recurrence (suspected implantation), and the other patient had recurrence in the residual thyroid gland. All patients with recurrence of adenoma underwent partial lobectomy at the initial operation. Three cancer patients had recurrent disease. Locoregional recurrence was observed in one patient and distant metastases in two patients (lung in one, lung and bone in one). One of the patients with distant metastasis died from the disease, and the other is alive with the disease. Tumor implantation was observed in patients with adenoma, so intraoperative handling of the tumor requires care. It also means that this tumor, even though benign, is aggressive in terms of proliferative activity. All patients with Hürthle cell tumor should be treated by total lobectomy at least. The outcome of the cancer patients was not as poor as in previous reports.

Original languageEnglish
Pages (from-to)1160-1163
Number of pages4
JournalWorld Journal of Surgery
Volume25
Issue number9
Publication statusPublished - 2001
Externally publishedYes

Fingerprint

Thyroid Gland
Neoplasms
Adenoma
Recurrence
Neoplasm Metastasis
Thyroglobulin
Bone and Bones
Lung

ASJC Scopus subject areas

  • Surgery

Cite this

Sugino, K., Ito, K., Mimura, T., Kameyama, K., Iwasaki, H., & Ito, K. (2001). Hürthle cell tumor of the thyroid: Analysis of 188 cases. World Journal of Surgery, 25(9), 1160-1163.

Hürthle cell tumor of the thyroid : Analysis of 188 cases. / Sugino, K.; Ito, K.; Mimura, T.; Kameyama, Kaori; Iwasaki, H.; Ito, K.

In: World Journal of Surgery, Vol. 25, No. 9, 2001, p. 1160-1163.

Research output: Contribution to journalArticle

Sugino, K, Ito, K, Mimura, T, Kameyama, K, Iwasaki, H & Ito, K 2001, 'Hürthle cell tumor of the thyroid: Analysis of 188 cases', World Journal of Surgery, vol. 25, no. 9, pp. 1160-1163.
Sugino K, Ito K, Mimura T, Kameyama K, Iwasaki H, Ito K. Hürthle cell tumor of the thyroid: Analysis of 188 cases. World Journal of Surgery. 2001;25(9):1160-1163.
Sugino, K. ; Ito, K. ; Mimura, T. ; Kameyama, Kaori ; Iwasaki, H. ; Ito, K. / Hürthle cell tumor of the thyroid : Analysis of 188 cases. In: World Journal of Surgery. 2001 ; Vol. 25, No. 9. pp. 1160-1163.
@article{7706cff28fc74812ac84affe25d07d39,
title = "H{\"u}rthle cell tumor of the thyroid: Analysis of 188 cases",
abstract = "We reviewed 188 cases of H{\"u}rthle cell tumor of the thyroid (HCT) between 1982 and 1996. There were 160 women and 28 men with a mean age of 51.8 years. Thirty-one of the patients had cancer, and the others had adenoma. Age, size of the primary tumor, and preoperative thyroglobulin level were not significantly different in the cancer and adenoma patients. The gender ratio, however, was significantly different (p < 0.05). Recurrent HCT was observed in three patients with adenoma. Two patients had subcutaneous recurrence (suspected implantation), and the other patient had recurrence in the residual thyroid gland. All patients with recurrence of adenoma underwent partial lobectomy at the initial operation. Three cancer patients had recurrent disease. Locoregional recurrence was observed in one patient and distant metastases in two patients (lung in one, lung and bone in one). One of the patients with distant metastasis died from the disease, and the other is alive with the disease. Tumor implantation was observed in patients with adenoma, so intraoperative handling of the tumor requires care. It also means that this tumor, even though benign, is aggressive in terms of proliferative activity. All patients with H{\"u}rthle cell tumor should be treated by total lobectomy at least. The outcome of the cancer patients was not as poor as in previous reports.",
author = "K. Sugino and K. Ito and T. Mimura and Kaori Kameyama and H. Iwasaki and K. Ito",
year = "2001",
language = "English",
volume = "25",
pages = "1160--1163",
journal = "World Journal of Surgery",
issn = "0364-2313",
publisher = "Springer New York",
number = "9",

}

TY - JOUR

T1 - Hürthle cell tumor of the thyroid

T2 - Analysis of 188 cases

AU - Sugino, K.

AU - Ito, K.

AU - Mimura, T.

AU - Kameyama, Kaori

AU - Iwasaki, H.

AU - Ito, K.

PY - 2001

Y1 - 2001

N2 - We reviewed 188 cases of Hürthle cell tumor of the thyroid (HCT) between 1982 and 1996. There were 160 women and 28 men with a mean age of 51.8 years. Thirty-one of the patients had cancer, and the others had adenoma. Age, size of the primary tumor, and preoperative thyroglobulin level were not significantly different in the cancer and adenoma patients. The gender ratio, however, was significantly different (p < 0.05). Recurrent HCT was observed in three patients with adenoma. Two patients had subcutaneous recurrence (suspected implantation), and the other patient had recurrence in the residual thyroid gland. All patients with recurrence of adenoma underwent partial lobectomy at the initial operation. Three cancer patients had recurrent disease. Locoregional recurrence was observed in one patient and distant metastases in two patients (lung in one, lung and bone in one). One of the patients with distant metastasis died from the disease, and the other is alive with the disease. Tumor implantation was observed in patients with adenoma, so intraoperative handling of the tumor requires care. It also means that this tumor, even though benign, is aggressive in terms of proliferative activity. All patients with Hürthle cell tumor should be treated by total lobectomy at least. The outcome of the cancer patients was not as poor as in previous reports.

AB - We reviewed 188 cases of Hürthle cell tumor of the thyroid (HCT) between 1982 and 1996. There were 160 women and 28 men with a mean age of 51.8 years. Thirty-one of the patients had cancer, and the others had adenoma. Age, size of the primary tumor, and preoperative thyroglobulin level were not significantly different in the cancer and adenoma patients. The gender ratio, however, was significantly different (p < 0.05). Recurrent HCT was observed in three patients with adenoma. Two patients had subcutaneous recurrence (suspected implantation), and the other patient had recurrence in the residual thyroid gland. All patients with recurrence of adenoma underwent partial lobectomy at the initial operation. Three cancer patients had recurrent disease. Locoregional recurrence was observed in one patient and distant metastases in two patients (lung in one, lung and bone in one). One of the patients with distant metastasis died from the disease, and the other is alive with the disease. Tumor implantation was observed in patients with adenoma, so intraoperative handling of the tumor requires care. It also means that this tumor, even though benign, is aggressive in terms of proliferative activity. All patients with Hürthle cell tumor should be treated by total lobectomy at least. The outcome of the cancer patients was not as poor as in previous reports.

UR - http://www.scopus.com/inward/record.url?scp=0034856238&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034856238&partnerID=8YFLogxK

M3 - Article

C2 - 11571953

AN - SCOPUS:0034856238

VL - 25

SP - 1160

EP - 1163

JO - World Journal of Surgery

JF - World Journal of Surgery

SN - 0364-2313

IS - 9

ER -